Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

New blood test may help in the fight against lung cancer

04.05.2010
A new blood test could increase the success of a popular lung cancer drug called erlotinib by allowing doctors select which patients will react positively to the drug.

Currently, patients with non-small cell lung cancer receive erlotinib after chemotherapy and other drugs have failed. But erlotinib will only shrink the tumour about 10 per cent of the time.

"This is a step in the right direction that will allow us to eventually personalize a patient's treatment," says Queen's University Oncology professor Lesley Seymour, who was the coordinating physician on the study. "At the moment, we give drugs to patients and if they respond, we are happy and continue the treatment. If they don't, we move on to another drug."

In addition to helping doctors select the best drug treatment for patients, tests such as these will reduce exposure to medical side effects like rash and diarrhea caused by erlotinib, and eliminate financial burdens for a drug that may not benefit the patient. Newer drugs such as erlotinib can cost thousands of dollars for a month of treatment.

The current research is a follow-up to an erlotinib clinical trial between 2001 and 2005 at the Queen's University-based National Cancer Institute of Canada Clinical Trials Group (NCIC CTG), which led to the approval of erlotinib in the treatment of non-small cell lung cancer.

In addition, blood and tissue samples collected in the original trials were used by David Carbone of the Vanderbilt-Ingram Cancer Center in Nashville to validate the blood tests. NCIC CTG and Queen's researchers also did the statistical analysis.

Professor Carbone presented his results on April 30 at the European Society for Medical Oncology Conference in Geneva, Switzerland.

Lung cancer is by far the deadliest form of cancer. There are 24,000 new cases of lung cancer diagnosed every year in Canada and 21,000 deaths.

Michael Onesi | EurekAlert!
Further information:
http://www.queensu.ca

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Nonstop Tranport of Cargo in Nanomachines

Max Planck researchers revel the nano-structure of molecular trains and the reason for smooth transport in cellular antennas.

Moving around, sensing the extracellular environment, and signaling to other cells are important for a cell to function properly. Responsible for those tasks...

Im Focus: UNH scientists help provide first-ever views of elusive energy explosion

Researchers at the University of New Hampshire have captured a difficult-to-view singular event involving "magnetic reconnection"--the process by which sparse particles and energy around Earth collide producing a quick but mighty explosion--in the Earth's magnetotail, the magnetic environment that trails behind the planet.

Magnetic reconnection has remained a bit of a mystery to scientists. They know it exists and have documented the effects that the energy explosions can...

Im Focus: A Chip with Blood Vessels

Biochips have been developed at TU Wien (Vienna), on which tissue can be produced and examined. This allows supplying the tissue with different substances in a very controlled way.

Cultivating human cells in the Petri dish is not a big challenge today. Producing artificial tissue, however, permeated by fine blood vessels, is a much more...

Im Focus: A Leap Into Quantum Technology

Faster and secure data communication: This is the goal of a new joint project involving physicists from the University of Würzburg. The German Federal Ministry of Education and Research funds the project with 14.8 million euro.

In our digital world data security and secure communication are becoming more and more important. Quantum communication is a promising approach to achieve...

Im Focus: Research icebreaker Polarstern begins the Antarctic season

What does it look like below the ice shelf of the calved massive iceberg A68?

On Saturday, 10 November 2018, the research icebreaker Polarstern will leave its homeport of Bremerhaven, bound for Cape Town, South Africa.

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

Optical Coherence Tomography: German-Japanese Research Alliance hosted Medical Imaging Conference

19.11.2018 | Event News

“3rd Conference on Laser Polishing – LaP 2018” Attracts International Experts and Users

09.11.2018 | Event News

On the brain’s ability to find the right direction

06.11.2018 | Event News

 
Latest News

Nonstop Tranport of Cargo in Nanomachines

20.11.2018 | Life Sciences

Researchers find social cultures in chimpanzees

20.11.2018 | Life Sciences

When AI and optoelectronics meet: Researchers take control of light properties

20.11.2018 | Physics and Astronomy

VideoLinks
Science & Research
Overview of more VideoLinks >>>