Part of the results of this research work has been included in a scientific paper of the August 2008 issue of the renowned international journal Bipolar Disorders. In addition, the Headlines review of the American Psychiatric Association has selected such article, among those published by the highest-impact psychiatric journal, as the relevant paper of the month as regards psychiatric disorders and their treatment.
To carry out this work, UGR researchers Luis Gutiérrez Rojas and Manuel Gurpegui Fernández de Legaria, together with other scientists, analysed 108 patients with BD, against a comparative group made up of 1,210 persons from a general population sample. Inside the group of patients, 48 of them were euthymic, this is, without active symptoms of the disease; the remaining 60 patients (non-euthymic) presented relevant symptoms during the evaluation.
BD, known in the past as manic-depressive psychosis, affects approximately 3 of every 100 persons and consists of suffering recurrent depression episodes (depressive phases) alternating with periods of euphoria (manic phases). The patients swing intensely (usually in weeks or months) from happiness to sadness, besides enjoying periods of normality (euthymia).
From this research we can also gather that BD patients who suffer a lower quality of mental life are those who started to suffer the disease before 20 years old, who have been suffering it for a longer time, who suffer the II subtype of the disease, who are dependent on tobacco and who are suffering depressive symptoms at present. In addition, the researchers from Granada have proved that having a high social support (such as that of the family) is connected with a better quality of life for the patient.
Besides it, their work has made clear that depressive symptoms (sadness, listlessness, tiredness, concentration difficulty, insomnia, poor appetite, etc.) have a higher impact in the quality of life than maniac symptoms (excessive self-esteem, lack on inhibition, verbosity, hyperactivity, increase of sexual appetite, etc.). And they also produce more disability or negative repercussion for working capacity andfamily and social life; this is probably due to that maniac symptoms are usually shorter in time and have a good response to medication, whereas depressive ones are usually more difficult to eliminate.
Reference: Luis Gutiérrez Rojas. Institute of Neurosciences of the University of Granada. Phone number: +34 958 24 07 04. E-mail: firstname.lastname@example.org
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