"The findings suggest that we should take another look at how we've been assessing the importance and the impact of these episodes," says Christopher Granger, M.D., a cardiologist at the Duke Heart Center and the senior author of the study.
Granger says that until recently, the medical community generally felt that an episode of arrhythmia (also known as fibrillation or tachycardia) – while worrisome – didn't complicate outcomes much for patients with blocked arteries because fast and effective treatments usually get blood flowing properly again. "But this study tells us that we were wrong. Now we know that an episode of ventricular fibrillation at any point significantly affects a patient's chance of a successful outcome."
The study appears in the May 6 issue of the Journal of the American Medical Association.
Researchers examined the records of 5745 heart attack patients enrolled in an international study of heart attack patients scheduled to undergo catheterization and stenting procedures between 2004 and 2006. They tracked which patients experienced arrhythmia, when it occurred, and what happened to patients afterwards.
They found that almost 6 percent of the patients experienced at least one episode of sustained ventricular arrhythmia either before or after the procedure.
They found that ventricular fibrillation occurred in 329 of the patients in the study group. Twenty-five of them experienced fibrillation before catheterization, 180 experienced it during the procedure and 117 afterwards. Investigators found that those who experienced fibrillation at any point were 3-fold more likely to die within the first three months after the procedure, when compared to those who did not have any arrhythmia.
Patients with larger heart attacks and who had less blood flow to the heart muscle were more likely than others to experience arrhythmias. A majority of the episodes occurred within two days of the PCI procedure.
"The study is important because it has helped us identify a subset of patients who may need extra time in the hospital under more intense monitoring in order to get them safely through that two-day period post-procedure when the vast majority of these arrhythmic episodes occur," says Rajendra Mehta, M.D., a cardiologist at the Duke Heart Center and the lead author of the study. Researchers say the chances of a serious episode of arrhythmia fall significantly after the initial 48 hours following catheterization.
Colleagues from Duke who contributed to the study include Renato Lopes, Paul Armstrong, Aijing Starr and Karen Pieper. Additional co-authors include Judith Hochman, from New York University School of Medicine; Petr Widimsky, from Kralovske Vinohrady University Hospital, Prague, Czech Republic; and Paul Armstrong, from the University of Alberta, Canada.
Michelle Gailiun | EurekAlert!
The genes are not to blame
20.07.2018 | Technische Universität München
Targeting headaches and tumors with nano-submarines
20.07.2018 | Universitätsmedizin der Johannes Gutenberg-Universität Mainz
A new manufacturing technique uses a process similar to newspaper printing to form smoother and more flexible metals for making ultrafast electronic devices.
The low-cost process, developed by Purdue University researchers, combines tools already used in industry for manufacturing metals on a large scale, but uses...
For the first time ever, scientists have determined the cosmic origin of highest-energy neutrinos. A research group led by IceCube scientist Elisa Resconi, spokesperson of the Collaborative Research Center SFB1258 at the Technical University of Munich (TUM), provides an important piece of evidence that the particles detected by the IceCube neutrino telescope at the South Pole originate from a galaxy four billion light-years away from Earth.
To rule out other origins with certainty, the team led by neutrino physicist Elisa Resconi from the Technical University of Munich and multi-wavelength...
For the first time a team of researchers have discovered two different phases of magnetic skyrmions in a single material. Physicists of the Technical Universities of Munich and Dresden and the University of Cologne can now better study and understand the properties of these magnetic structures, which are important for both basic research and applications.
Whirlpools are an everyday experience in a bath tub: When the water is drained a circular vortex is formed. Typically, such whirls are rather stable. Similar...
Physicists working with Roland Wester at the University of Innsbruck have investigated if and how chemical reactions can be influenced by targeted vibrational excitation of the reactants. They were able to demonstrate that excitation with a laser beam does not affect the efficiency of a chemical exchange reaction and that the excited molecular group acts only as a spectator in the reaction.
A frequently used reaction in organic chemistry is nucleophilic substitution. It plays, for example, an important role in in the synthesis of new chemical...
Optical spectroscopy allows investigating the energy structure and dynamic properties of complex quantum systems. Researchers from the University of Würzburg present two new approaches of coherent two-dimensional spectroscopy.
"Put an excitation into the system and observe how it evolves." According to physicist Professor Tobias Brixner, this is the credo of optical spectroscopy....
13.07.2018 | Event News
12.07.2018 | Event News
03.07.2018 | Event News
20.07.2018 | Power and Electrical Engineering
20.07.2018 | Information Technology
20.07.2018 | Materials Sciences