The study led by Dr. Ross D. Feldman, a clinical scientist with the Robarts Research Institute at The University of Western Ontario recommends a simplified and more effective method of treating hypertension using low doses of single pill combinations, rather than multiple pills. The "Simplified Treatment Intervention to Control Hypertension" (STITCH) study is in the April edition of the journal Hypertension.
STITCH involved 2,104 patients with high blood pressure at 45 family practices in southwestern Ontario, Canada. Researchers wanted to see if there are simpler ways to help patients (and their doctors) reduce their blood pressure to goal levels than by following national guidelines which can be complicated. Feldman's study suggests that the majority of recently-diagnosed patients might better be served starting with a half tablet of a single pill combination drug (e.g. an ACE-inhibitor/diuretic or Angiotensin receptor blocker/diuretic combination) than the regular starting dose of a single drug.
"The nature of hypertension management has changed. It's much more aggressive, and complex, leading to hundreds of recommendations on how to manage high blood pressure," says Feldman, the R.W. Gunton Professor of Therapeutics at Western. "This should be a call to hypertensive patients to go to their family physicians to be prescribed these single pill combinations. It makes both the patients' and doctors' lives easier."
The proper diagnosis and treatment of high blood pressure can cut your risk of stroke by up to 40% and heart attack by up to 25%.
Kathy Wallis | EurekAlert!
Study tracks inner workings of the brain with new biosensor
16.08.2018 | Rheinische Friedrich-Wilhelms-Universität Bonn
Foods of the future
15.08.2018 | Georg-August-Universität Göttingen
New design tool automatically creates nanostructure 3D-print templates for user-given colors
Scientists present work at prestigious SIGGRAPH conference
Most of the objects we see are colored by pigments, but using pigments has disadvantages: such colors can fade, industrial pigments are often toxic, and...
Scientists at the University of California, Los Angeles present new research on a curious cosmic phenomenon known as "whistlers" -- very low frequency packets...
Scientists develop first tool to use machine learning methods to compute flow around interactively designable 3D objects. Tool will be presented at this year’s prestigious SIGGRAPH conference.
When engineers or designers want to test the aerodynamic properties of the newly designed shape of a car, airplane, or other object, they would normally model...
Researchers from TU Graz and their industry partners have unveiled a world first: the prototype of a robot-controlled, high-speed combined charging system (CCS) for electric vehicles that enables series charging of cars in various parking positions.
Global demand for electric vehicles is forecast to rise sharply: by 2025, the number of new vehicle registrations is expected to reach 25 million per year....
Proteins must be folded correctly to fulfill their molecular functions in cells. Molecular assistants called chaperones help proteins exploit their inbuilt folding potential and reach the correct three-dimensional structure. Researchers at the Max Planck Institute of Biochemistry (MPIB) have demonstrated that actin, the most abundant protein in higher developed cells, does not have the inbuilt potential to fold and instead requires special assistance to fold into its active state. The chaperone TRiC uses a previously undescribed mechanism to perform actin folding. The study was recently published in the journal Cell.
Actin is the most abundant protein in highly developed cells and has diverse functions in processes like cell stabilization, cell division and muscle...
17.08.2018 | Event News
08.08.2018 | Event News
27.07.2018 | Event News
17.08.2018 | Physics and Astronomy
17.08.2018 | Information Technology
17.08.2018 | Life Sciences