Research from doctors at The Ohio State University Wexner Medical Center finds a new "virtual biopsy" allows them to definitively diagnose cysts in the pancreas with unprecedented accuracy. This means they can eliminate precancerous cysts and potentially save lives.
The current standard involves testing the fluid inside the cysts. It correctly identifies them as benign or precancerous 71% of the time. Researchers found that when the virtual biopsy is added to the standard of care, the diagnostic accuracy jumps to 97%. The study is published in Clinical Gastroenterology and Hepatology and was recently presented at the American Pancreatic Association's Annual Meeting.
Dr. Somashekar Krishna performs an endomicroscopy at The Ohio State University Wexner Medical Center. This new diagnostic method provides doctors with a "virtual biopsy" that allows them to accurately diagnose dangerous pancreatic cysts before they develop into cancer.
Credit: The Ohio State University Wexner Medical Center
"Pancreatic cysts are common, and it can be difficult to distinguish the benign cysts from those destined to become cancerous, but this procedure allows us to do that quickly and with confidence," said Dr. Somashekar Krishna, a gastroenterologist and lead author of the study.
"We hope that, at the end of the day, we are saving lives either by diagnosing pancreatic cancer early on before it develops into cancer, or we are preventing unnecessary surgery of a benign, harmless pancreatic cyst."
The diagnostic method tested in the study provides doctors with a microscopic view of the cyst wall, which is produced by a tiny scope that emits laser light inside the cyst. This allows doctors to determine almost immediately if it is precancerous.
"Many times, we are able to tell the patient right after the procedure, 'You have a precancerous cyst, and we need to send you to the surgeon to have it removed'," said Krishna, who is an associate professor in Ohio State's College of Medicine and is also affiliated with The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC - James).
A majority of patients get diagnosed with pancreatic cysts incidentally when getting a MRI or CT scan for another reason. Nearly 40% of MRIs done of the abdomen reveal pancreatic cysts and the chance of having them increases with age.
More than 45,000 Americans die of pancreatic cancer each year, making it the third-leading cause of cancer deaths. Patients usually don't have symptoms until the cancer is advanced, making early diagnosis and treatment a challenge.
Ohio State researchers are now working to train doctors at hospitals nationwide to perform this new diagnostic method and read the images provided by the scope to catch dangerous cysts and prevent pancreatic cancer for more patients. They're also working to develop artificial intelligence that will flag cases that are likely precancerous so doctors can act quickly.
Alyssa Moody | EurekAlert!
Smartphone cameras can speed up urinary tract infection diagnosis
08.01.2020 | University of Bath
Livestream from the Digestive System: Magnet-Guided Camera Capsules for More Pleasant Gastroscopies
06.01.2020 | Fraunhofer-Institut für Zuverlässigkeit und Mikrointegration IZM
Styrofoam or copper - both materials have very different properties with regard to their ability to conduct heat. Scientists at the Max Planck Institute for Polymer Research (MPI-P) in Mainz and the University of Bayreuth have now jointly developed and characterized a novel, extremely thin and transparent material that has different thermal conduction properties depending on the direction. While it can conduct heat extremely well in one direction, it shows good thermal insulation in the other direction.
Thermal insulation and thermal conduction play a crucial role in our everyday lives - from computer processors, where it is important to dissipate heat as...
In order to advance the transfer of research developments from the field of quantum sensor technology into industrial applications, an application laboratory is being established at Fraunhofer IAF. This will enable interested companies and especially regional SMEs and start-ups to evaluate the innovation potential of quantum sensors for their specific requirements. Both the state of Baden-Württemberg and the Fraunhofer-Gesellschaft are supporting the four-year project with one million euros each.
The application laboratory is being set up as part of the Fraunhofer lighthouse project »QMag«, short for quantum magnetometry. In this project, researchers...
Microtubules, filamentous structures within the cell, are required for many important processes, including cell division and intracellular transport. A...
Researchers from the University Hospital Zurich, ETH Zurich, Wyss Zurich and the University of Zurich have developed a machine that repairs injured human livers and keep them alive outside the body for one week. This breakthrough may increase the number of available organs for transplantation saving many lives of patients with severe liver diseases or cancer.
Until now, livers could be stored safely outside the body for only a few hours. With the novel perfusion technology, livers - and even injured livers - can now...
A balloon-borne scientific instrument designed to study the origin of cosmic rays is taking its second turn high above the continent of Antarctica three and a half weeks after its launch.
SuperTIGER (Super Trans-Iron Galactic Element Recorder) is designed to measure the rare, heavy elements in cosmic rays that hold clues about their origins...
16.01.2020 | Event News
15.01.2020 | Event News
07.01.2020 | Event News
17.01.2020 | Life Sciences
17.01.2020 | Power and Electrical Engineering
17.01.2020 | Life Sciences