Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Siemens’ New Biograph mCT PET-CT System Enables Greater Diagnostic Certainty

28.11.2011
The new PET-CT scanner offers accurate, reproducible quantification in molecular imaging, for results that redefine clinical decision-making

At the 97th Scientific Assembly and Annual Meeting of the Radiological Society of North America (RSNA), November 27 to December 2 in Chicago, USA, Siemens Healthcare introduced the next-generation Biograph mCT, its positron emission tomography-computed tomography (PET-CT) scanner that enables precise measurement of metabolic processes and data quantification, including the assessment of neurological disease and cancerous tissue, as well as cardiac blood flow (perfusion). Technological innovations and intelligent software solutions within the new PET-CT result in quantitative assessments that are accurate and consistent. Siemens presents with the new Biograph mCT another paradigm in PET-CT to further strengthen the company’s innovative power and competitiveness within the recently introduced global initiative “Agenda 2013”.


“By bringing accuracy and reproducibility to quantification in PET, we can more precisely characterize cancer lesions, allowing for better staging and monitoring of the change in activity over time for more accurate assessment of treatment response”, said Jerry Froelich, MD, FACR, Loken Professor of Radiological Sciences and head of molecular imaging and nuclear medicine at the University of Minnesota, Minneapolis. “In cardiology, being able to measure absolute myocardial blood flow allows for accurate assessment of multi-vessel disease.

In neurology, the potential is huge. The ability to noninvasively assess the brain can improve the diagnosis and therefore management of patients presenting signs of Alzheimer's disease.” Siemens incorporated this clinical requirement in the new Biograph mCT to support physicians in treating many oncological, cardiological and neurological diseases – not only through earlier, more exact diagnosis, but also in therapy planning and precise monitoring of disease progression.

The additional information provided will help enable physicians to make decisions with high certainty and initiate more patient-tailored therapies. The level of measurement and quantification to be offered by the new Biograph mCT has special significance for the diagnosis of neurodegenerative diseases, such as dementia.

With the latest Biograph mCT and potential new PET biomarkers1, reliable imaging of beta-amyloid plaque in the brain may be possible, providing additional information to aid in the diagnosis of dementia, potentially slowing disease progression through earlier care. The most frequently diagnosed form of dementia is Alzheimer’s disease, which currently affects an estimated 35.6 million people worldwide, with predictions of as many as 115.4 million patients having the disease by 2050.2

Technical Innovations

With conventional technology, clinicians face the issue of variability in quantitative results due to software and hardware challenges. Intelligently engineered to overcome these technical and procedural obstacles, the new Biograph mCT is designed to offer accurate and reproducible quantification in PET•CT imaging by ensuring that each element of the imaging chain is optimized – with an emphasis on the finest volumetric image resolution on the market3, daily system calibration, accuracy of attenuation correction using automated co-registration algorithms and more automated, user-independent and reproducible SUV calculation methods for daily clinical practice.

The new Biograph mCT incorporates the Siemens unique OptisoHD (High-Definition) Detector System, which will feature a fine volumetric resolution4 of only 87 mm3. Other innovative technologies include Time of Flight (TOF) and HD (High-Definition) PET, ensuring fast, precise images with minimum radiation dose. With Siemens Quanti•QC, daily system normalization can be performed overnight, calibrating and tuning the system to precisely the right specifications, facilitating consistent and optimal performance, day after day.

SMART (Siemens Molecular & Anatomical Registration Technologies) address the traditional problem of inherent scanner drift and inaccurate attenuation correction through misregistration of anatomical and functional images.

To facilitate accurate attenuation correction and reliable quantitative measurements, the new Biograph mCT will feature a unique patient handling system designed to virtually eliminates differential deflection, as well as Auto Cardiac Registration that automatically aligns CT and PET heart images and reduces variability between users. SMART also offers a new form of attenuation correction for neurological images that no longer requires CT data.5

Advanced syngo clinical applications provide essential tools to obtain quantifiable measurements in neurology, cardiology and oncology imaging. SUVpeak, new in the syngo.via oncology engine, provides consistent and reproducible quantitative assessments of hot spots. Myocardial Blood Flow (MBF) can be used as an absolute quantification method to assess balanced disease in all areas of the heart. And an exciting quantitative tool in neurology, the syngo.PET Neuro6 applications, automatically registers brain data to a normals database to assist in the assessment of neurological disorders.

The new Biograph mCT is currently under review by the FDA.

Preparing for a Changing Healthcare Market

Agenda 2013 is a global initiative to further strengthen Healthcare Sector's innovative power and competitiveness. Four fields of action have been defined: Innovation, Competitiveness, Regional Footprint, and People Development, with specific measures to be implemented over the next two years.

The here mentioned product/features are not commercially available. Due to regulatory reasons, its future availability in any country cannot be guaranteed. Please contact your local Siemens organization for further details. The outcomes achieved by the Siemens customers described herein were achieved in the customer's unique setting. Since there is no "typical" hospital and many variables exist, e.g., hospital size, case mix, level of IT adoption, there can be no guarantee that others will achieve the same results.

The Siemens Healthcare Sector is one of the world's largest suppliers to the healthcare industry and a trendsetter in medical imaging, laboratory diagnostics, medical information technology and hearing aids. Siemens offers its customers products and solutions for the entire range of patient care from a single source – from prevention and early detection to diagnosis, and on to treatment and aftercare. By optimizing clinical workflows for the most common diseases, Siemens also makes healthcare faster, better and more cost-effective. Siemens Healthcare employs some 51,000 employees worldwide and operates around the world. In fiscal year 2011 (to September 30), the Sector posted revenue of 12.5 billion euros and profit of around 1.3 billion euros.

Bianca Braun | Siemens Healthcare
Further information:
http://www.siemens.com/healthcare

More articles from Medical Engineering:

nachricht Faster detection of atrial fibrillation thanks to smartwatch
18.03.2019 | Universität Greifswald

nachricht A peek into lymph nodes
15.03.2019 | Tohoku University

All articles from Medical Engineering >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: The taming of the light screw

DESY and MPSD scientists create high-order harmonics from solids with controlled polarization states, taking advantage of both crystal symmetry and attosecond electronic dynamics. The newly demonstrated technique might find intriguing applications in petahertz electronics and for spectroscopic studies of novel quantum materials.

The nonlinear process of high-order harmonic generation (HHG) in gases is one of the cornerstones of attosecond science (an attosecond is a billionth of a...

Im Focus: Magnetic micro-boats

Nano- and microtechnology are promising candidates not only for medical applications such as drug delivery but also for the creation of little robots or flexible integrated sensors. Scientists from the Max Planck Institute for Polymer Research (MPI-P) have created magnetic microparticles, with a newly developed method, that could pave the way for building micro-motors or guiding drugs in the human body to a target, like a tumor. The preparation of such structures as well as their remote-control can be regulated using magnetic fields and therefore can find application in an array of domains.

The magnetic properties of a material control how this material responds to the presence of a magnetic field. Iron oxide is the main component of rust but also...

Im Focus: Self-healing coating made of corn starch makes small scratches disappear through heat

Due to the special arrangement of its molecules, a new coating made of corn starch is able to repair small scratches by itself through heat: The cross-linking via ring-shaped molecules makes the material mobile, so that it compensates for the scratches and these disappear again.

Superficial micro-scratches on the car body or on other high-gloss surfaces are harmless, but annoying. Especially in the luxury segment such surfaces are...

Im Focus: Stellar cartography

The Potsdam Echelle Polarimetric and Spectroscopic Instrument (PEPSI) at the Large Binocular Telescope (LBT) in Arizona released its first image of the surface magnetic field of another star. In a paper in the European journal Astronomy & Astrophysics, the PEPSI team presents a Zeeman- Doppler-Image of the surface of the magnetically active star II Pegasi.

A special technique allows astronomers to resolve the surfaces of faraway stars. Those are otherwise only seen as point sources, even in the largest telescopes...

Im Focus: Heading towards a tsunami of light

Researchers at Chalmers University of Technology and the University of Gothenburg, Sweden, have proposed a way to create a completely new source of radiation. Ultra-intense light pulses consist of the motion of a single wave and can be described as a tsunami of light. The strong wave can be used to study interactions between matter and light in a unique way. Their research is now published in the scientific journal Physical Review Letters.

"This source of radiation lets us look at reality through a new angle - it is like twisting a mirror and discovering something completely different," says...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

International Modelica Conference with 330 visitors from 21 countries at OTH Regensburg

11.03.2019 | Event News

Selection Completed: 580 Young Scientists from 88 Countries at the Lindau Nobel Laureate Meeting

01.03.2019 | Event News

LightMAT 2019 – 3rd International Conference on Light Materials – Science and Technology

28.02.2019 | Event News

 
Latest News

Laser processing is a matter for the head – LZH at the Hannover Messe 2019

25.03.2019 | Trade Fair News

A Varied Menu

25.03.2019 | Life Sciences

‘Time Machine’ heralds new era

25.03.2019 | Information Technology

VideoLinks
Science & Research
Overview of more VideoLinks >>>