Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Laser therapy can aggravate skin cancer

23.11.2009
High irradiances of low-level laser therapy (LLLT) should not be used over melanomas. Researchers writing in the open access journal BMC Cancer studied the pain relieving, anti-inflammatory 'cold laser', finding that it caused increased tumour growth in a mouse model of skin cancer.

Jan M. Bjordal from Bergen University College, Norway worked with a team of Brazilian researchers to carry out the in vitro and in vivo experiments. He said, "LLLT has gained increasing popularity as a treatment for soft tissue injuries and joint conditions. However, there is a shortage of evidence, especially in vivo evidence, about the effects of LLLT in malignant conditions such as melanoma".

Bjordal and his colleagues applied LLLT to cancer cultures and to mice injected with melanoma cells. Although the treatment did not cause any significant changes in the cell cultures, direct irradiation of the tumor with high-dose LLLT caused a significant increase in tumor mass volume and considerable histological alterations, indicating a worsening of the cancer, in the mice. The researchers write, "A high irradiance (2.5W/cm2) combined with high dose of 1050 J/cm2, can stimulate melanoma tumor growth with distinct histological features in vivo".

"It is important that this contraindication is implemented into clinical practice so that LLLT can remain a safe treatment", says Bjordal.

LLLT was pioneered in the 1970s, when it was discovered that light from low-intensity lasers causes cells to proliferate more rapidly. It is marketed as a treatment for hair-loss, pain management, sports medicine and skin care – among many other things. Home-treatment sets are available online for unsupervised use.

1. The effect of low-level laser irradiation (Ga-Al-AsP - 660nm) on in vitro and in vivo melanoma
Lucio Frigo, Juliana SS Luppi, Giovani M Favero, Durvanei A Maria, Socrates C Penna, Jan M Bjordal, Rene J Bensadoun and Rodrigo Alvaro Lopes Martins

BMC Cancer (in press)

2. BMC Cancer is an open access journal publishing original peer-reviewed research articles in all aspects of cancer research, including the pathophysiology, prevention, diagnosis and treatment of cancers. The journal welcomes submissions concerning molecular and cellular biology, genetics, epidemiology, and clinical trials. BMC Cancer (ISSN 1471-2407) is indexed/tracked/covered by PubMed, MEDLINE, CAS, EMBASE, Scopus, Current Contents, Thomson Reuters (ISI) and Google Scholar.

3. BioMed Central (http://www.biomedcentral.com/) is an STM (Science, Technology and Medicine) publisher which has pioneered the open access publishing model. All peer-reviewed research articles published by BioMed Central are made immediately and freely accessible online, and are licensed to allow redistribution and reuse. BioMed Central is part of Springer Science+Business Media, a leading global publisher in the STM sector.

Graeme Baldwin | EurekAlert!
Further information:
http://www.biomedcentral.com

More articles from Medical Engineering:

nachricht MoreGrasp: significant research results in the field of thought-controlled grasp neuroprosthetics
17.09.2018 | Technische Universität Graz

nachricht Wearable ultrasound patch monitors blood pressure deep inside body
13.09.2018 | University of California - San Diego

All articles from Medical Engineering >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Patented nanostructure for solar cells: Rough optics, smooth surface

Thin-film solar cells made of crystalline silicon are inexpensive and achieve efficiencies of a good 14 percent. However, they could do even better if their shiny surfaces reflected less light. A team led by Prof. Christiane Becker from the Helmholtz-Zentrum Berlin (HZB) has now patented a sophisticated new solution to this problem.

"It is not enough simply to bring more light into the cell," says Christiane Becker. Such surface structures can even ultimately reduce the efficiency by...

Im Focus: New soft coral species discovered in Panama

A study in the journal Bulletin of Marine Science describes a new, blood-red species of octocoral found in Panama. The species in the genus Thesea was discovered in the threatened low-light reef environment on Hannibal Bank, 60 kilometers off mainland Pacific Panama, by researchers at the Smithsonian Tropical Research Institute in Panama (STRI) and the Centro de Investigación en Ciencias del Mar y Limnología (CIMAR) at the University of Costa Rica.

Scientists established the new species, Thesea dalioi, by comparing its physical traits, such as branch thickness and the bright red colony color, with the...

Im Focus: New devices based on rust could reduce excess heat in computers

Physicists explore long-distance information transmission in antiferromagnetic iron oxide

Scientists have succeeded in observing the first long-distance transfer of information in a magnetic group of materials known as antiferromagnets.

Im Focus: Finding Nemo's genes

An international team of researchers has mapped Nemo's genome

An international team of researchers has mapped Nemo's genome, providing the research community with an invaluable resource to decode the response of fish to...

Im Focus: Graphene enables clock rates in the terahertz range

Graphene is considered a promising candidate for the nanoelectronics of the future. In theory, it should allow clock rates up to a thousand times faster than today’s silicon-based electronics. Scientists from the Helmholtz Zentrum Dresden-Rossendorf (HZDR) and the University of Duisburg-Essen (UDE), in cooperation with the Max Planck Institute for Polymer Research (MPI-P), have now shown for the first time that graphene can actually convert electronic signals with frequencies in the gigahertz range – which correspond to today’s clock rates – extremely efficiently into signals with several times higher frequency. The researchers present their results in the scientific journal “Nature”.

Graphene – an ultrathin material consisting of a single layer of interlinked carbon atoms – is considered a promising candidate for the nanoelectronics of the...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

One of the world’s most prominent strategic forums for global health held in Berlin in October 2018

03.09.2018 | Event News

4th Intelligent Materials - European Symposium on Intelligent Materials

27.08.2018 | Event News

LaserForum 2018 deals with 3D production of components

17.08.2018 | Event News

 
Latest News

Making better use of enzymes: a new research project at Jacobs University

19.09.2018 | Life Sciences

Light provides spin

19.09.2018 | Physics and Astronomy

Enjoying virtual-reality-entertainment without headache or motion sickness

19.09.2018 | Information Technology

VideoLinks
Science & Research
Overview of more VideoLinks >>>