Cytocompatibility studies of organic light-emitting diodes (OLEDs) have been carried out on cell cultures for the first time at the Fraunhofer Institute for Organic Electronics, Electron Beam and Plasma Technology FEP to test how well OLEDs are tolerated by cells. The results offer promising prospects for the use of OLEDs in the medical field, such as in light therapy. The findings were published in a white paper entitled “Preliminary cytocompatibility studies for encapsulated OLEDs” and likewise be presented at the 4th Industry Partners Day of the Fraunhofer FEP in Dresden on September 28, 2016.
Light therapy is an important means of promoting the healing of wounds. Difficult and protracted healing processes of the skin, such as are due to chronic and infected wounds, present a challenge for treating physicians and can be positively affected by exposure to light.
The Fraunhofer FEP in Dresden has years of experience researching processes, technologies, and applications for flexible OLEDs. In order to be able to employ these area light sources for potential medical applications though, any potential toxic effects caused by the constituent materials must be precluded. No such studies on what is termed the cytocompatibility of flexible OLEDs were known of to date.
Now for the first time, the cytocompatibility of flexible OLED systems has been evaluated in a pilot study. Dr. Schönfelder, head of the Medical Applications Research Group at Fraunhofer FEP, recounts enthusiastically: “Even after electrical operation and exposure to mechanical loading by bending, no toxic substances able to alter cells diffused from the OLEDs.”
As a follow-on, studies on the influence of OLED light were conducted using in vitro cell cultures from the skin and the immune system suffering from specified damage. Initial results indicate effects of accelerated auto-recovery that could be the foundation for future therapeutic applications.
Division Director Dr. Christian May in looking ahead remarks: “We need long-term studies yet to be able to guaranty cytocompatibility during exposure to OLED light. Safe electrical connections, power supplies, control circuitry, and component perimeter seals are important aspects that we are dedicating ourselves to – before direct application to the patient is allowed.”
Detailed findings can be reviewed in the white paper entitled „Preliminary cytocompatibility studies for encapsulated OLEDs“ at http://s.fhg.de/N8L and were presented by Dr. Jacqueline Hauptmann in her talk entitled “OLED light application in medicine and cytotoxicity of the materials” during the 4th Industry Partners Day devoted to medical topics at the Fraunhofer FEP on September 28, 2016.
Registration and program materials can be found at www.fep.fraunhofer.de/ipd. Sponsorship opportunities at the event as well as participation via info kiosks are available.
Annett Arnold | Fraunhofer-Institut für Organische Elektronik, Elektronenstrahl- und Plasmatechnik FEP
A 15-minute scan could help diagnose brain damage in newborns
15.11.2018 | Imperial College London
NIH scientists combine technologies to view the retina in unprecedented detail
14.11.2018 | NIH/National Eye Institute
Researchers at the University of New Hampshire have captured a difficult-to-view singular event involving "magnetic reconnection"--the process by which sparse particles and energy around Earth collide producing a quick but mighty explosion--in the Earth's magnetotail, the magnetic environment that trails behind the planet.
Magnetic reconnection has remained a bit of a mystery to scientists. They know it exists and have documented the effects that the energy explosions can...
Biochips have been developed at TU Wien (Vienna), on which tissue can be produced and examined. This allows supplying the tissue with different substances in a very controlled way.
Cultivating human cells in the Petri dish is not a big challenge today. Producing artificial tissue, however, permeated by fine blood vessels, is a much more...
Faster and secure data communication: This is the goal of a new joint project involving physicists from the University of Würzburg. The German Federal Ministry of Education and Research funds the project with 14.8 million euro.
In our digital world data security and secure communication are becoming more and more important. Quantum communication is a promising approach to achieve...
On Saturday, 10 November 2018, the research icebreaker Polarstern will leave its homeport of Bremerhaven, bound for Cape Town, South Africa.
When choosing materials to make something, trade-offs need to be made between a host of properties, such as thickness, stiffness and weight. Depending on the application in question, finding just the right balance is the difference between success and failure
Now, a team of Penn Engineers has demonstrated a new material they call "nanocardboard," an ultrathin equivalent of corrugated paper cardboard. A square...
09.11.2018 | Event News
06.11.2018 | Event News
23.10.2018 | Event News
16.11.2018 | Health and Medicine
16.11.2018 | Life Sciences
16.11.2018 | Life Sciences