Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Wood on our Skin

09.10.2019

Physiological parameters in our blood can be determined without painful punctures. Empa researchers are currently working with a Canadian team to develop flexible, biocompatible nanocellulose sensors that can be attached to the skin. The 3D-printed analytic chips made of renewable raw materials will even be biodegradable in future.

The idea of measuring parameters that are relevant for our health via the skin has already taken hold in medical diagnostics. Diabetics, for example, can painlessly determine their blood sugar level with a sensor instead of having to prick their fingers.


Empa researcher Gilberto Siqueira demonstrates the newly printed nanocellulose circuit. After a subsequent drying, the material can be further processed.

Empa


Using a 3D printer, the nanocellulose "ink" is applied to a carrier plate. Silver particles provide the electrical conductivity of the material.

Empa

Empa researchers, together with scientists from Canada, have now produced a novel flexible sensor that lies on the skin surface and is biocompatible because it is made of nanocellulose.

A transparent foil made of wood

Nanocellulose is an inexpensive, renewable raw material, which can be obtained in form of crystals and fibers, for example from wood. However, the original appearance of a tree no longer has anything to do with the gelatinous substance, which can consist of cellulose nanocrystals and cellulose nanofibers.

Other sources of the material are bacteria, algae or residues from agricultural production. Thus, nanocellulose is not only relatively easy and sustainable to obtain. Its mechanical properties also make the "super pudding" an interesting product. For instance, new composite materials based on nanocellulose can be developed that could be used as surface coatings, transparent packaging films or even to produce everyday objects like beverage bottles.

Researchers at Empa's Cellulose & Wood Materials lab and Woo Soo Kim from the Simon Fraser University in Burnaby, Canada, are also focusing on another feature of nanocellulose: biocompatibility. Since the material is obtained from natural resources, it is particularly suitable for biomedical research.

With the aim of producing biocompatible sensors that can measure important metabolic values, the researchers used nanocellulose as an "ink" in 3D printing processes. To make the sensors electrically conductive, the ink was mixed with silver nanowires. The researchers determined the exact ratio of nanocellulose and silver threads so that a three-dimensional network could form.

Just like spaghetti – only a wee bit smaller

It turned out that cellulose nanofibers are better suited than cellulose nanocrystals to produce a cross-linked matrix with the tiny silver wires. "Cellulose nanofibers are flexible similar to cooked spaghetti, but with a diameter of only about 20 nanometers and a length of just a few micrometers," explains Empa researcher Gilberto Siqueira.

The team finally succeeded in developing sensors that measure medically relevant metabolic parameters such as the concentration of calcium, potassium and ammonium ions. The electrochemical skin sensor sends its results wirelessly to a computer for further data processing. The tiny biochemistry lab on the skin is only half a millimeter thin.

While the tiny biochemistry lab on the skin – which is only half a millimeter thin – is capable of determining ion concentrations specifically and reliably, the researchers are already working on an updated version. "In the future, we want to replace the silver particles with another conductive material, for example on the basis of carbon compounds," Siqueira explains. This would make the medical nanocellulose sensor not only biocompatible, but also completely biodegradable.

Wissenschaftliche Ansprechpartner:

Dr. Gustav Nyström
Cellulose & Wood Materials
Phone +41 58 765 4583
Gustav.nystroem@empa.ch

Dr. Siqueira Gilberto De Freitas
Cellulose & Wood Materials
Phone +41 58 765 47 82
Gilberto.siqueira@empa.ch


Editor / Media Contact

Dr. Andrea Six
Communication
Phone +41 58 765 61 33
redaktion@empa.ch

Originalpublikation:

T Kim, C Bao, M Hausmann, G Siqueira, T Zimmermann, W Kim; 3D Printed Disposable Wireless Ion Sensors with Biocompatible Cellulose Composites; Advanced Electronic Materials (2019); doi: 10.1002/aelm.201800778

Rainer Klose | Empa - Eidgenössische Materialprüfungs- und Forschungsanstalt
Further information:
https://www.empa.ch/web/s604/nanocellulose-sensor-eq65

More articles from Life Sciences:

nachricht Researchers discover vaccine to strengthen the immune system of plants
24.01.2020 | Westfälische Wilhelms-Universität Münster

nachricht Brain-cell helpers powered by norepinephrine during fear-memory formation
24.01.2020 | RIKEN

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Integrate Micro Chips for electronic Skin

Researchers from Dresden and Osaka present the first fully integrated flexible electronics made of magnetic sensors and organic circuits which opens the path towards the development of electronic skin.

Human skin is a fascinating and multifunctional organ with unique properties originating from its flexible and compliant nature. It allows for interfacing with...

Im Focus: Dresden researchers discover resistance mechanism in aggressive cancer

Protease blocks guardian function against uncontrolled cell division

Researchers of the Carl Gustav Carus University Hospital Dresden at the National Center for Tumor Diseases Dresden (NCT/UCC), together with an international...

Im Focus: New roles found for Huntington's disease protein

Crucial role in synapse formation could be new avenue toward treatment

A Duke University research team has identified a new function of a gene called huntingtin, a mutation of which underlies the progressive neurodegenerative...

Im Focus: A new look at 'strange metals'

For years, a new synthesis method has been developed at TU Wien (Vienna) to unlock the secrets of "strange metals". Now a breakthrough has been achieved. The results have been published in "Science".

Superconductors allow electrical current to flow without any resistance - but only below a certain critical temperature. Many materials have to be cooled down...

Im Focus: Programmable nests for cells

KIT researchers develop novel composites of DNA, silica particles, and carbon nanotubes -- Properties can be tailored to various applications

Using DNA, smallest silica particles, and carbon nanotubes, researchers of Karlsruhe Institute of Technology (KIT) developed novel programmable materials....

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

11th Advanced Battery Power Conference, March 24-25, 2020 in Münster/Germany

16.01.2020 | Event News

Laser Colloquium Hydrogen LKH2: fast and reliable fuel cell manufacturing

15.01.2020 | Event News

„Advanced Battery Power“- Conference, Contributions are welcome!

07.01.2020 | Event News

 
Latest News

Researchers discover vaccine to strengthen the immune system of plants

24.01.2020 | Life Sciences

Brain-cell helpers powered by norepinephrine during fear-memory formation

24.01.2020 | Life Sciences

Engineered capillaries model traffic in tiny blood vessels

24.01.2020 | Life Sciences

VideoLinks
Science & Research
Overview of more VideoLinks >>>