Collaborative Research Center at the University of Freiburg enters its third and final funding period
The German Research Foundation (Deutsche Forschungsgemeinschaft, DFG) has approved the renewal application for the Collaborative Research Center (CRC, Sonderforschungsbereich, SFB) 850 “Control of Cell Motility in Morphogenesis, Cancer Invasion and Metastasis”. The CRC 850 has been running since January 1, 2010 and will enter its third and final funding period starting at the beginning of 2018.
The DFG has assured a total of 12.7 million euros for the coming four years. Researchers from the Faculties of Biology and Medicine at the University of Freiburg along with the German Cancer Consortium, partner site Freiburg and the Max Planck Institute of Immunobiology and Epigenetics are collaborating in this CRC, which hitherto has brought forth more than 180 scientific publications.
Prof. Dr. Christoph Peters, Director of the Institute of Molecular Medicine and Cell Research and Scientific Director of Comprehensive Cancer Center Freiburg (CCCF) is the spokesperson.
Cell motility describes the cells’ ability to move actively. Uncontrolled cell motility is one of the key characteristics of malignant tumors. It allows the tumor cells to invade neighboring tissue, spread through the body and form colonies or so-called metastases in foreign organs. These metastases pose a huge problem in cancer medicine and are responsible for the majority of cancer related deaths.
Cell motility is controlled by central signaling pathways that are active during embryonic development and may be reactivated in malignant cancer cells. They play an essential role in the formation and spread of tumors.
The aim of the SFB 850 is to better understand the molecular mechanisms of these signaling pathways and to apply this knowledge to control the motility of cells, for example, through already existing drugs. These insights may also serve as basis for the development of new therapeutic strategies for inhibiting the invasion of cancer cells into healthy tissue and thereby to prevent the formation and growth of metastases.
The scientific background of the participating groups is wide ranging - from basic research in developmental biology to clinical cancer research in the CCCF, enabling a direct review of the clinical relevance of the obtained findings.
Prof. Dr. Christoph Peters
Institute of Molecular Medicine and Cell Research
University of Freiburg
Christoph Peters is the spokesperson for the special research area "Control of Cell Mobility in Morphogenesis, Cancer Invasion and Metastasis." Photo: Britt Schilling/University Medical Center Freiburg
Rudolf-Werner Dreier | Albert-Ludwigs-Universität Freiburg im Breisgau
New findings help to better calculate the oceans’ contribution to climate regulation
14.11.2018 | Jacobs University Bremen gGmbH
How algae and carbon fibers could sustainably reduce the athmospheric carbon dioxide concentration
14.11.2018 | Technische Universität München
Biochips have been developed at TU Wien (Vienna), on which tissue can be produced and examined. This allows supplying the tissue with different substances in a very controlled way.
Cultivating human cells in the Petri dish is not a big challenge today. Producing artificial tissue, however, permeated by fine blood vessels, is a much more...
Faster and secure data communication: This is the goal of a new joint project involving physicists from the University of Würzburg. The German Federal Ministry of Education and Research funds the project with 14.8 million euro.
In our digital world data security and secure communication are becoming more and more important. Quantum communication is a promising approach to achieve...
On Saturday, 10 November 2018, the research icebreaker Polarstern will leave its homeport of Bremerhaven, bound for Cape Town, South Africa.
When choosing materials to make something, trade-offs need to be made between a host of properties, such as thickness, stiffness and weight. Depending on the application in question, finding just the right balance is the difference between success and failure
Now, a team of Penn Engineers has demonstrated a new material they call "nanocardboard," an ultrathin equivalent of corrugated paper cardboard. A square...
Physicists at ETH Zurich demonstrate how errors that occur during the manipulation of quantum system can be monitored and corrected on the fly
The field of quantum computation has seen tremendous progress in recent years. Bit by bit, quantum devices start to challenge conventional computers, at least...
09.11.2018 | Event News
06.11.2018 | Event News
23.10.2018 | Event News
14.11.2018 | Materials Sciences
14.11.2018 | Health and Medicine
14.11.2018 | Life Sciences