Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Sonicating sperm -- the future of male contraception

30.01.2012
The ideal male contraceptive would be inexpensive, reliable, and reversible. It would need to be long acting but have few side effects.

New research published in BioMed Central's open access journal Reproductive Biology and Endocrinology used commercially available therapeutic ultrasound equipment to reduce sperm counts of male rats to levels which would result in infertility in humans.

Ultrasound's potential as a male contraceptive was first reported nearly 40 years ago. However the equipment used is now outdated and no longer available. Researchers from the Department of Pediatrics at the University of North Carolina School of Medicine used these experiments as a starting point to see if modern ultrasound equipment usually used for physical therapy could be used as a male contraceptive.

The team led by James Tsuruta found that by rotating high frequency (3MHz) ultrasound around the testes they were able to cause uniform depletion of germ cells throughout the testes. The best results were seen using two sessions consisting of 15 minutes ultrasound, two days apart. Saline was used to provide conduction between the ultrasound transducer and skin, and the testes were warmed to 37 degrees centigrade. Together this reduced sperm to a Sperm Count Index of zero (3 million motile sperm per cauda epididymis).

The World Health Organization has defined oligospermia (low sperm concentration) as less than 15 million sperm per ml. Dr Tsuruta explained, "Unlike humans, rats remain fertile even with extremely low sperm counts. However, our non-invasive ultrasound treatment reduced sperm reserves in rats far below levels normally seen in fertile men (95% of fertile men have more than 39 million sperm in their ejaculate). However further studies are required to determine how long the contraceptive effect lasts and if it is safe to use multiple times."

Notes to Editors

1. Therapeutic ultrasound as a potential male contraceptive: power, frequency and temperature required to deplete rat testes of meiotic cells and epididymides of sperm determined using a commercially available system
James K Tsuruta, Paul A Dayton, Caterina M Gallippi, Michael G O'Rand, Michael A Streicker, Ryan C Gessner, Thomas S Gregory, Erick JR Silva, Katherine G Hamil, Glenda J Moser and David C Sokal

Reproductive Biology and Endocrinology (in press)

Please name the journal in any story you write. If you are writing for the web, please link to the article. All articles are available free of charge, according to BioMed Central's open access policy.

Article citation and URL available on request at press@biomedcentral.com on the day of publication.

2. Reproductive Biology and Endocrinology (RB&E) is an open access, peer-reviewed, online journal that aims to act as a forum for the dissemination of results from excellent research in the reproductive sciences.

3. BioMed Central (http://www.biomedcentral.com/) is an STM (Science, Technology and Medicine) publisher which has pioneered the open access publishing model. All peer-reviewed research articles published by BioMed Central are made immediately and freely accessible online, and are licensed to allow redistribution and reuse. BioMed Central is part of Springer Science+Business Media, a leading global publisher in the STM sector.

Dr. Hilary Glover | EurekAlert!
Further information:
http://www.biomedcentral.com

More articles from Life Sciences:

nachricht First use of vasoprotective antibody in cardiogenic shock
17.05.2019 | Deutsches Zentrum für Herz-Kreislauf-Forschung e.V.

nachricht A nerve cell serves as a “single” for studies
15.05.2019 | Rheinische Friedrich-Wilhelms-Universität Bonn

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Self-repairing batteries

UTokyo engineers develop a way to create high-capacity long-life batteries

Engineers at the University of Tokyo continually pioneer new ways to improve battery technology. Professor Atsuo Yamada and his team recently developed a...

Im Focus: Quantum Cloud Computing with Self-Check

With a quantum coprocessor in the cloud, physicists from Innsbruck, Austria, open the door to the simulation of previously unsolvable problems in chemistry, materials research or high-energy physics. The research groups led by Rainer Blatt and Peter Zoller report in the journal Nature how they simulated particle physics phenomena on 20 quantum bits and how the quantum simulator self-verified the result for the first time.

Many scientists are currently working on investigating how quantum advantage can be exploited on hardware already available today. Three years ago, physicists...

Im Focus: Accelerating quantum technologies with materials processing at the atomic scale

'Quantum technologies' utilise the unique phenomena of quantum superposition and entanglement to encode and process information, with potentially profound benefits to a wide range of information technologies from communications to sensing and computing.

However a major challenge in developing these technologies is that the quantum phenomena are very fragile, and only a handful of physical systems have been...

Im Focus: A step towards probabilistic computing

Working group led by physicist Professor Ulrich Nowak at the University of Konstanz, in collaboration with a team of physicists from Johannes Gutenberg University Mainz, demonstrates how skyrmions can be used for the computer concepts of the future

When it comes to performing a calculation destined to arrive at an exact result, humans are hopelessly inferior to the computer. In other areas, humans are...

Im Focus: Recording embryonic development

Scientists develop a molecular recording tool that enables in vivo lineage tracing of embryonic cells

The beginning of new life starts with a fascinating process: A single cell gives rise to progenitor cells that eventually differentiate into the three germ...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

SEMANTiCS 2019 brings together industry leaders and data scientists in Karlsruhe

29.04.2019 | Event News

Revered mathematicians and computer scientists converge with 200 young researchers in Heidelberg!

17.04.2019 | Event News

First dust conference in the Central Asian part of the earth’s dust belt

15.04.2019 | Event News

 
Latest News

Discovering unusual structures from exception using big data and machine learning techniques

17.05.2019 | Materials Sciences

ALMA discovers aluminum around young star

17.05.2019 | Physics and Astronomy

A new iron-based superconductor stabilized by inter-block charger transfer

17.05.2019 | Materials Sciences

VideoLinks
Science & Research
Overview of more VideoLinks >>>