Dr Paul Schofield of the Department of Physiology Development and Neuroscience at the University of Cambridge chaired an influential meeting on this issue in Rome in May of this year, supported by the European Commission-funded CASIMIR project (www.casimir.org.uk).
CASIMIR is tasked to look at the factors inhibiting the free exchange of data and materials between investigators using the mouse as a model system to study human disease.
The meeting was attended by senior representatives of major international research sponsors, leading scientific journals, intellectual property and technology transfer specialists and sociologists. It endorsed the need for global coordination and effective policies to reduce barriers to the free exchange of data and materials between scientists to ensure the sharing of research results and materials to maximize research benefit, optimize the use of research sponsorship and more effectively manage and optimize the dissemination of biological research results through academic or commercial channels.
Significant consensus was achieved, and the results of this important meeting are published in Nature this week. Research on mice as models for human diseases is of major current international importance and is essential until better alternatives are found if the full societal benefits of the elucidation of the human genome are to be achieved. Better sharing of data and existing mice will reduce the need to generate new model organisms and avoid unnecessary duplication.
One of the key findings of this study is the negative impact of over-restrictive licensing by some Universities and research agencies of genetically engineered mice and embryonic stem cells - the outputs of this research - and the failure of researchers to efficiently share their research results and materials by depositing their mice and ES cells in the major public repositories now in place in Europe, North America, Japan and Australia.
The meeting set an agenda for community discussion - The Rome Agenda - also free to access online, which outlines guidelines to enable sharing of biomaterials under the least restrictive terms, avoiding restrictive material transfer agreements (MTAs) where possible. The meeting also recommended increased investment in public databases and mouse repositories to keep pace with the rapid acceleration of research in this area.
Dr Schofield said: "Sharing of data and biological resources in the post-genomic age has become crucial to the advancement of the biomedical sciences. The agreements reached in Rome will help to coordinate the development of policies and infrastructure in international science resulting in huge advantages to the research community and better value for money to the public agencies and charities who fund the majority of this research."
The Rome Agenda is intended to spark community discussion on this subject. Paul Schofield, Tania Bubela (University of Alberta, Edmonton, Canada) and other meeting participants will respond to reader comments in two online forums on Nature Network which will go live after the embargo has lifted: http://network.nature.com/groups/naturenewsandopinion/forum/topics/5433 http://network.nature.com/groups/naturenewsandopinion/forum/topics/5434
Notes to Editors:
1. The commentary piece "Post-publication sharing of data and tools" is scheduled for publication in the journal Nature on 09 September 2009.
2. Further recent discussions of some of these issues can be found on the Nature website: http://www.nature.com/news/2009/090603/full/459620a.html http://www.nature.com/nature/journal/v459/n7248/full/459752a.html
Dr. Paul Schofield | EurekAlert!
Breakthrough in designing a better Salmonella vaccine
25.09.2018 | University of California - Davis
Proof of Concept: Gene therapy for mitochondrial diseases
25.09.2018 | Max-Planck-Institut für Biologie des Alterns
The Fraunhofer FEP has been involved in developing processes and equipment for cleaning, sterilization, and surface modification for decades. The CleanHand Network for development of systems and technologies to clean surfaces, materials, and objects was established in May 2018 to bundle the expertise of many partnering organizations. As a partner in the CleanHand Network, Fraunhofer FEP will present the Network and current research topics of the Institute in the field of hygiene and cleaning at the parts2clean trade fair, October 23-25, 2018 in Stuttgart, at the booth of the Fraunhofer Cleaning Technology Alliance (Hall 5, Booth C31).
Test reports and studies on the cleanliness of European motorway rest areas, hotel beds, and outdoor pools increasingly appear in the press, especially during...
The building blocks of matter in our universe were formed in the first 10 microseconds of its existence, according to the currently accepted scientific picture. After the Big Bang about 13.7 billion years ago, matter consisted mainly of quarks and gluons, two types of elementary particles whose interactions are governed by quantum chromodynamics (QCD), the theory of strong interaction. In the early universe, these particles moved (nearly) freely in a quark-gluon plasma.
This is a joint press release of University Muenster and Heidelberg as well as the GSI Helmholtzzentrum für Schwerionenforschung in Darmstadt.
Then, in a phase transition, they combined and formed hadrons, among them the building blocks of atomic nuclei, protons and neutrons. In the current issue of...
Thin-film solar cells made of crystalline silicon are inexpensive and achieve efficiencies of a good 14 percent. However, they could do even better if their shiny surfaces reflected less light. A team led by Prof. Christiane Becker from the Helmholtz-Zentrum Berlin (HZB) has now patented a sophisticated new solution to this problem.
"It is not enough simply to bring more light into the cell," says Christiane Becker. Such surface structures can even ultimately reduce the efficiency by...
A study in the journal Bulletin of Marine Science describes a new, blood-red species of octocoral found in Panama. The species in the genus Thesea was discovered in the threatened low-light reef environment on Hannibal Bank, 60 kilometers off mainland Pacific Panama, by researchers at the Smithsonian Tropical Research Institute in Panama (STRI) and the Centro de Investigación en Ciencias del Mar y Limnología (CIMAR) at the University of Costa Rica.
Scientists established the new species, Thesea dalioi, by comparing its physical traits, such as branch thickness and the bright red colony color, with the...
Scientists have succeeded in observing the first long-distance transfer of information in a magnetic group of materials known as antiferromagnets.
21.09.2018 | Event News
03.09.2018 | Event News
27.08.2018 | Event News
25.09.2018 | Health and Medicine
25.09.2018 | Health and Medicine
25.09.2018 | Information Technology