Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Scientists at University of Colorado Anschutz Medical Campus discover new fat cell

03.08.2010
The fat cell may pose health threat

As if fat weren't troublesome enough, a research team at the University of Colorado School of Medicine has discovered a new type of fat cell with potentially harmful characteristics.

The new fat cells arise from stem cells in the bone marrow that travel through the blood stream to fat tissue. They are termed bone marrow progenitor-derived adipocytes. The discovery also revealed that male and female subjects accumulate the new fat cells differently. The research also may help to explain the link between types of obesity and heart disease and other illnesses.

The findings by Dwight J. Klemm, PhD, and Susan M. Majka, PhD, are reported this week in the Proceedings of the National Academy of Science of the United States of America.

"Our results explain why the accumulation of fat in certain body locations harms health," Klemm said.

According to Majka, the research "may identify ways to prevent those adverse effects as people age or gain weight."

The body stores energy in fat – either white or brown cells. But over time too much fat can cause health issues. Previously, the researchers at the University of Colorado Anschutz Medical Campus had traced certain fat cells back to bone marrow. It appeared likely that a type of stem cell (the hematopoietic cell) was getting into the blood stream and settling somewhere else.

The latest research, which used laboratory mice but applies to humans, demonstrates that is the case. It shows that these stem cells travel through the blood stream into fat tissue and tend to accumulate in deep abdominal fat, primarily of females. This new type of fat may affect the body's ability to dispose of fats and sugars, and produces inflammatory problems. The results also help explain why fat in different parts of the body behaves differently. The research team now is detailing the health threats these fat cells cause and looking for ways to halt the formation and accumulation of harmful fat.

Faculty at the University of Colorado's School of Medicine work to advance science and improve care. These faculty members include physicians, educators and scientists at University of Colorado Hospital, The Children's Hospital, Denver Health, National Jewish Health, and the Denver Veterans Affairs Medical Center. Degrees offered by the School of Medicine include doctor of medicine, doctor of physical therapy, and masters of physician assistant studies. The School is located on the Anschutz Medical Campus, one of four campuses in the University of Colorado system. For additional news and information, please visit the UC Denver newsroom online.

The University of Colorado Anschutz Medical Campus is a model for the type of interdisciplinary research in translational medicine that will take basic discovery "from the bench to the bedside."

David Kelly | EurekAlert!
Further information:
http://www.ucdenver.edu

More articles from Life Sciences:

nachricht Climate Impact Research in Hannover: Small Plants against Large Waves
17.08.2018 | Leibniz Universität Hannover

nachricht First transcription atlas of all wheat genes expands prospects for research and cultivation
17.08.2018 | Leibniz-Institut für Pflanzengenetik und Kulturpflanzenforschung

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Color effects from transparent 3D-printed nanostructures

New design tool automatically creates nanostructure 3D-print templates for user-given colors
Scientists present work at prestigious SIGGRAPH conference

Most of the objects we see are colored by pigments, but using pigments has disadvantages: such colors can fade, industrial pigments are often toxic, and...

Im Focus: Unraveling the nature of 'whistlers' from space in the lab

A new study sheds light on how ultralow frequency radio waves and plasmas interact

Scientists at the University of California, Los Angeles present new research on a curious cosmic phenomenon known as "whistlers" -- very low frequency packets...

Im Focus: New interactive machine learning tool makes car designs more aerodynamic

Scientists develop first tool to use machine learning methods to compute flow around interactively designable 3D objects. Tool will be presented at this year’s prestigious SIGGRAPH conference.

When engineers or designers want to test the aerodynamic properties of the newly designed shape of a car, airplane, or other object, they would normally model...

Im Focus: Robots as 'pump attendants': TU Graz develops robot-controlled rapid charging system for e-vehicles

Researchers from TU Graz and their industry partners have unveiled a world first: the prototype of a robot-controlled, high-speed combined charging system (CCS) for electric vehicles that enables series charging of cars in various parking positions.

Global demand for electric vehicles is forecast to rise sharply: by 2025, the number of new vehicle registrations is expected to reach 25 million per year....

Im Focus: The “TRiC” to folding actin

Proteins must be folded correctly to fulfill their molecular functions in cells. Molecular assistants called chaperones help proteins exploit their inbuilt folding potential and reach the correct three-dimensional structure. Researchers at the Max Planck Institute of Biochemistry (MPIB) have demonstrated that actin, the most abundant protein in higher developed cells, does not have the inbuilt potential to fold and instead requires special assistance to fold into its active state. The chaperone TRiC uses a previously undescribed mechanism to perform actin folding. The study was recently published in the journal Cell.

Actin is the most abundant protein in highly developed cells and has diverse functions in processes like cell stabilization, cell division and muscle...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

LaserForum 2018 deals with 3D production of components

17.08.2018 | Event News

Within reach of the Universe

08.08.2018 | Event News

A journey through the history of microscopy – new exhibition opens at the MDC

27.07.2018 | Event News

 
Latest News

Smallest transistor worldwide switches current with a single atom in solid electrolyte

17.08.2018 | Physics and Astronomy

Robots as Tools and Partners in Rehabilitation

17.08.2018 | Information Technology

Climate Impact Research in Hannover: Small Plants against Large Waves

17.08.2018 | Life Sciences

VideoLinks
Science & Research
Overview of more VideoLinks >>>