Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Researchers Find Novel Technique to Study Living Cells

04.03.2009
An international team of scientists, co-led by a University of Kentucky researcher, has developed a technique for imaging nanostructures on the surface of living cells.

The team, whose principal investigators include Gregory Frolenkov of the UK Department of Physiology, developed “hopping probe ion conductance microscopy,” in which a nanoscale probe “hops” over the surface of a cell in an action similar to a sewing machine needle. They published their development in this week’s edition of Nature Methods.

The technique permitted the researchers to visualize the surface of a complex living cell at a nanoscale resolution, which was previously possible only in dead cells using electron microscopy.

“Now we can see nanostructures such as individual protein or protein complexes in a living cell and probe their function. Many diseases affect the cell surface.

Therefore, we expect that our technique, together with emerging high-resolution imaging techniques looking inside the cell, will clarify the mechanisms of a number of diseases, the same way as a regular optical microscope revolutionized medicine centuries ago,” Frolenkov said.

The other co-principal investigators on the project are Yuri E. Korchev of the Imperial College London Division of Medicine in London, United Kingdom, and David Klenerman of Cambridge University’s Department of Chemistry in Cambridge, United Kingdom. Also participating in the research was Ruben Stepanyan of the UK Department of Physiology, part of the UK College of Medicine.

Dan Adkins | Newswise Science News
Further information:
http://w2.uky.edu/UKPR/
http://www.uky.edu

More articles from Life Sciences:

nachricht Bioenergy cropland expansion could be as bad for biodiversity as climate change
11.12.2018 | Senckenberg Forschungsinstitut und Naturmuseen

nachricht How glial cells develop in the brain from neural precursor cells
11.12.2018 | Universitätsmedizin der Johannes Gutenberg-Universität Mainz

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Topological material switched off and on for the first time

Key advance for future topological transistors

Over the last decade, there has been much excitement about the discovery, recognised by the Nobel Prize in Physics only two years ago, that there are two types...

Im Focus: Researchers develop method to transfer entire 2D circuits to any smooth surface

What if a sensor sensing a thing could be part of the thing itself? Rice University engineers believe they have a two-dimensional solution to do just that.

Rice engineers led by materials scientists Pulickel Ajayan and Jun Lou have developed a method to make atom-flat sensors that seamlessly integrate with devices...

Im Focus: Three components on one chip

Scientists at the University of Stuttgart and the Karlsruhe Institute of Technology (KIT) succeed in important further development on the way to quantum Computers.

Quantum computers one day should be able to solve certain computing problems much faster than a classical computer. One of the most promising approaches is...

Im Focus: Substitute for rare earth metal oxides

New Project SNAPSTER: Novel luminescent materials by encapsulating phosphorescent metal clusters with organic liquid crystals

Nowadays energy conversion in lighting and optoelectronic devices requires the use of rare earth oxides.

Im Focus: A bit of a stretch... material that thickens as it's pulled

Scientists have discovered the first synthetic material that becomes thicker - at the molecular level - as it is stretched.

Researchers led by Dr Devesh Mistry from the University of Leeds discovered a new non-porous material that has unique and inherent "auxetic" stretching...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

New Plastics Economy Investor Forum - Meeting Point for Innovations

10.12.2018 | Event News

EGU 2019 meeting: Media registration now open

06.12.2018 | Event News

Expert Panel on the Future of HPC in Engineering

03.12.2018 | Event News

 
Latest News

Electronic evidence of non-Fermi liquid behaviors in an iron-based superconductor

11.12.2018 | Physics and Astronomy

Topological material switched off and on for the first time

11.12.2018 | Materials Sciences

NIST's antenna evaluation method could help boost 5G network capacity and cut costs

11.12.2018 | Information Technology

VideoLinks
Science & Research
Overview of more VideoLinks >>>