Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Researchers develop micro Petri dish for massively parallel growth and screening of micro-organisms

09.11.2007
Scientists of Top Institute Food & Nutrition, Wageningen University and Research Centre, NIZO food research and the MESA+ Institute for Nanotechnology in the Netherlands have developed a new technology that allows unprecedented miniaturisation of the growth of micro-organisms.

On a chip with the size of a postage stamp, more than one million cultures can be grown in parallel which opens up a wide range of uses from diagnosis of infection to the improvement of industrial bacteria. The corresponding paper ‘The micro Petri dish, a million-well chip for the culture and high-throughput screening of microorganisms’ has been published in Proceedings of the National Academy of Science (online Early Edition) on 7th November 2007.

A team of microbiologists and micro-engineering experts developed the chip that has the potential to meet the automation and miniaturisation needs of modern microbiology. The development of high-throughput bacterial screening methods has been slow in an era of advancements in fields like genomics and proteomics. The ‘micro Petri dish’ allows growth assays to catch up with other high-throughput technologies in the life sciences. ‘Besides that, the chip is readily manufactured, cheap and easy-to-use in a standard microbiology lab’ explain researchers Colin Ingham (WUR) and Johan van Hylckama Vlieg (NIZO).

The innovation is in the micro-engineering of a unique porous ceramic to create millions of wells that serve as growth areas for micro-organisms. The micron-scale wells of the chip can be regarded as an array of millions of “micro Petri dishes”, where bacteria or yeasts are efficiently supplied with nutrients from below through a porous membrane. By using this chip, assays for the detection and growth of micro-organisms will become faster and cheaper whilst it permits larger screening operations for improved industrial strains than have been possible to date.

TI Food and Nutrition (www.tifn.nl) is a unique public/private partnership that generates vision on scientific breakthroughs in food and nutrition, resulting in the development of innovative products and technologies that respond to consumer demands for safe, tasty and healthy foods. 'This project, a close collaboration between biotechnologists and nanotechnologists, is a good example of the trans-disciplinary approach we have developed', says Jan Sikkema, programme director at Top Institute Food and Nutrition.

Jac Niessen | alfa
Further information:
http://www.wur.nl

Further reports about: Micro Petri dish Screening develop micro-organisms

More articles from Life Sciences:

nachricht Molecular motors run in unison in a metal-organic framework
20.03.2019 | University of Groningen

nachricht Active substance from plant slows down aggressive eye cancer
20.03.2019 | Rheinische Friedrich-Wilhelms-Universität Bonn

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Self-healing coating made of corn starch makes small scratches disappear through heat

Due to the special arrangement of its molecules, a new coating made of corn starch is able to repair small scratches by itself through heat: The cross-linking via ring-shaped molecules makes the material mobile, so that it compensates for the scratches and these disappear again.

Superficial micro-scratches on the car body or on other high-gloss surfaces are harmless, but annoying. Especially in the luxury segment such surfaces are...

Im Focus: Stellar cartography

The Potsdam Echelle Polarimetric and Spectroscopic Instrument (PEPSI) at the Large Binocular Telescope (LBT) in Arizona released its first image of the surface magnetic field of another star. In a paper in the European journal Astronomy & Astrophysics, the PEPSI team presents a Zeeman- Doppler-Image of the surface of the magnetically active star II Pegasi.

A special technique allows astronomers to resolve the surfaces of faraway stars. Those are otherwise only seen as point sources, even in the largest telescopes...

Im Focus: Heading towards a tsunami of light

Researchers at Chalmers University of Technology and the University of Gothenburg, Sweden, have proposed a way to create a completely new source of radiation. Ultra-intense light pulses consist of the motion of a single wave and can be described as a tsunami of light. The strong wave can be used to study interactions between matter and light in a unique way. Their research is now published in the scientific journal Physical Review Letters.

"This source of radiation lets us look at reality through a new angle - it is like twisting a mirror and discovering something completely different," says...

Im Focus: Revealing the secret of the vacuum for the first time

New research group at the University of Jena combines theory and experiment to demonstrate for the first time certain physical processes in a quantum vacuum

For most people, a vacuum is an empty space. Quantum physics, on the other hand, assumes that even in this lowest-energy state, particles and antiparticles...

Im Focus: Sussex scientists one step closer to a clock that could replace GPS and Galileo

Physicists in the EPic Lab at University of Sussex make crucial development in global race to develop a portable atomic clock

Scientists in the Emergent Photonics Lab (EPic Lab) at the University of Sussex have made a breakthrough to a crucial element of an atomic clock - devices...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

International Modelica Conference with 330 visitors from 21 countries at OTH Regensburg

11.03.2019 | Event News

Selection Completed: 580 Young Scientists from 88 Countries at the Lindau Nobel Laureate Meeting

01.03.2019 | Event News

LightMAT 2019 – 3rd International Conference on Light Materials – Science and Technology

28.02.2019 | Event News

 
Latest News

Molecular motors run in unison in a metal-organic framework

20.03.2019 | Life Sciences

Active substance from plant slows down aggressive eye cancer

20.03.2019 | Life Sciences

Novel sensor system improves reliability of high-temperature humidity measurements

20.03.2019 | Trade Fair News

VideoLinks
Science & Research
Overview of more VideoLinks >>>