The mathematicians, funded by the Biotechnology and Biological Sciences Research Council (BBSRC), will investigate how the different cellular components of the immune system work together and devise a theoretical and computational model that can be used by immunologists, mathematicians, computer scientists, physicists and engineers.
The model promises to help a multi-disciplinary research community work together to bring about medical advances for patients. The project, the Immunology Imaging and Modelling (I2M) Network, is highlighted in the quarterly research highlights magazine of the Biotechnology and Biological Sciences Research Council (BBSRC) this week.
The immune system is one of the most fascinating and complex systems in the human body and scientists still do not fully understand how it works. Immunology has traditionally been a qualitative science, describing the cellular and molecular components of the immune system and their functions. However, to advance our understanding of how the body fights disease there is a pressing need to better understand how the components work together as a whole and provide this information in a quantitative format which can be accessed by the entire scientific community.
Dr Carmen Molína-Paris, network co-ordinator and researcher at the University of Leeds, explains: "A multi and cross-disciplinary, cohesive and active approach is urgently required. The ability to track parasites and cells in real time using novel imaging techniques is allowing exciting new insights and will help us measure the interactions between the different parts of the immune system. This will provide a theoretical and computational model of the immune system, giving a complete picture that researchers from across all disciplines can refer to and draw upon.
"Mathematical immunology is maturing into a discipline where modelling helps everyone to interpret data and resolve controversies. Most importantly, it suggests novel experiments allowing for better and more quantitative interpretations."
Steve Visscher, interim Chief Executive of BBSRC commented: "The new insight that this model will provide will naturally benefit the patient with the advances in healthcare it will lead to. BBSRC is committed to developing an active and cohesive cross-disciplinary community at the mathematics biology interface to enable a more quantitative and predictive biology."
Michelle Kilfoyle | alfa
Mass spectrometry sheds new light on thallium poisoning cold case
14.12.2018 | University of Maryland
Protein involved in nematode stress response identified
14.12.2018 | University of Illinois College of Agricultural, Consumer and Environmental Sciences
The more objects we make "smart," from watches to entire buildings, the greater the need for these devices to store and retrieve massive amounts of data quickly without consuming too much power.
Millions of new memory cells could be part of a computer chip and provide that speed and energy savings, thanks to the discovery of a previously unobserved...
What if, instead of turning up the thermostat, you could warm up with high-tech, flexible patches sewn into your clothes - while significantly reducing your...
A widely used diabetes medication combined with an antihypertensive drug specifically inhibits tumor growth – this was discovered by researchers from the University of Basel’s Biozentrum two years ago. In a follow-up study, recently published in “Cell Reports”, the scientists report that this drug cocktail induces cancer cell death by switching off their energy supply.
The widely used anti-diabetes drug metformin not only reduces blood sugar but also has an anti-cancer effect. However, the metformin dose commonly used in the...
A research team from the University of Zurich has developed a new drone that can retract its propeller arms in flight and make itself small to fit through narrow gaps and holes. This is particularly useful when searching for victims of natural disasters.
Inspecting a damaged building after an earthquake or during a fire is exactly the kind of job that human rescuers would like drones to do for them. A flying...
Over the last decade, there has been much excitement about the discovery, recognised by the Nobel Prize in Physics only two years ago, that there are two types...
12.12.2018 | Event News
10.12.2018 | Event News
06.12.2018 | Event News
14.12.2018 | Power and Electrical Engineering
14.12.2018 | Physics and Astronomy
14.12.2018 | Physics and Astronomy