Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Progenika Biopharma presents a biochip that guarantees safety in blood transfusions

05.07.2007
The Basque biotechnology company, Progenika Biopharma, devoted to research and development in personalised medicine, have presented a DNA biochip, known as BLOODchip, which greatly eliminates the risk of adverse reactions due to incompatibility in blood groups between donor and receptor in blood transfusions.

With the aim of guaranteeing safety during blood transfusions, Progenika has developed and validated 1,000 clinical samples in cooperation with the principal European blood banks. Concretely, the validation of these samples was 99.8%, considerably higher than that produced using the current serology technique, which produces an error of 3%.

Thus, BLOODchip is currently the safest and most precise technique for genetically determining blood groups, enabling the reduction of adverse reactions in blood transfusions.

Two different techniques are currently used to detect possible incompatibilities in blood transfusions: the serological method and DNA sequencing. The serological technique has a limited capacity and does not allow the detection of 3% of the incompatibilities existing. DNA sequencing, while overcoming this drawback of the serological method, is however a slow and costly system.

Progenika has developed BLOODchip to respond to the disadvantages of the current systems. In this way, the totality of blood group incompatibilities are detected in a safer, quicker and more specific analytical process than with the serological technique. Moreover, its cost is twenty times less than DNA sequencing, which enables its generalized and routine use in all blood transfusions.

The BLOODchip is the result of research within the remit of the European Union IV Framework Programme and undertaken by Progenika in collaboration with the principal European blood banks.

It should be pointed out that Progenika Biopharma has developed and patented various products that are already on the market for several types of diagnosis (for diagnoses, prognoses and the prediction of and response to treatment of human diseases). So, in 2004 Progenika launched the LIPOchip on to the market, for the diagnosis of Family Hypercholesterolemia, the first biochip with the CE label and on sale since 2004. Progenika currently has 3 products that are at a development phase and which will finalise at the end of the year.

Progenika has managed to become the international technological leader in the field of developing genetic biochips. Biochips enable the simultaneous analysis of genetic variables, multiplying the capacity of conventional techniques for the diagnosis of illness, prognosticating its aggressiveness and progression and predicting the response of the patient to treatment.

Irati Kortabitarte | alfa
Further information:
http://www.basqueresearch.com/berria_irakurri.asp?Berri_Kod=1387&hizk=I

Further reports about: BLOODchip BioPharma Biochip DNA Progenika serological technique transfusions

More articles from Life Sciences:

nachricht Climate Impact Research in Hannover: Small Plants against Large Waves
17.08.2018 | Leibniz Universität Hannover

nachricht First transcription atlas of all wheat genes expands prospects for research and cultivation
17.08.2018 | Leibniz-Institut für Pflanzengenetik und Kulturpflanzenforschung

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Color effects from transparent 3D-printed nanostructures

New design tool automatically creates nanostructure 3D-print templates for user-given colors
Scientists present work at prestigious SIGGRAPH conference

Most of the objects we see are colored by pigments, but using pigments has disadvantages: such colors can fade, industrial pigments are often toxic, and...

Im Focus: Unraveling the nature of 'whistlers' from space in the lab

A new study sheds light on how ultralow frequency radio waves and plasmas interact

Scientists at the University of California, Los Angeles present new research on a curious cosmic phenomenon known as "whistlers" -- very low frequency packets...

Im Focus: New interactive machine learning tool makes car designs more aerodynamic

Scientists develop first tool to use machine learning methods to compute flow around interactively designable 3D objects. Tool will be presented at this year’s prestigious SIGGRAPH conference.

When engineers or designers want to test the aerodynamic properties of the newly designed shape of a car, airplane, or other object, they would normally model...

Im Focus: Robots as 'pump attendants': TU Graz develops robot-controlled rapid charging system for e-vehicles

Researchers from TU Graz and their industry partners have unveiled a world first: the prototype of a robot-controlled, high-speed combined charging system (CCS) for electric vehicles that enables series charging of cars in various parking positions.

Global demand for electric vehicles is forecast to rise sharply: by 2025, the number of new vehicle registrations is expected to reach 25 million per year....

Im Focus: The “TRiC” to folding actin

Proteins must be folded correctly to fulfill their molecular functions in cells. Molecular assistants called chaperones help proteins exploit their inbuilt folding potential and reach the correct three-dimensional structure. Researchers at the Max Planck Institute of Biochemistry (MPIB) have demonstrated that actin, the most abundant protein in higher developed cells, does not have the inbuilt potential to fold and instead requires special assistance to fold into its active state. The chaperone TRiC uses a previously undescribed mechanism to perform actin folding. The study was recently published in the journal Cell.

Actin is the most abundant protein in highly developed cells and has diverse functions in processes like cell stabilization, cell division and muscle...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

LaserForum 2018 deals with 3D production of components

17.08.2018 | Event News

Within reach of the Universe

08.08.2018 | Event News

A journey through the history of microscopy – new exhibition opens at the MDC

27.07.2018 | Event News

 
Latest News

Smallest transistor worldwide switches current with a single atom in solid electrolyte

17.08.2018 | Physics and Astronomy

Robots as Tools and Partners in Rehabilitation

17.08.2018 | Information Technology

Climate Impact Research in Hannover: Small Plants against Large Waves

17.08.2018 | Life Sciences

VideoLinks
Science & Research
Overview of more VideoLinks >>>