The degree is the first of its kind in the country, fulfilling a need to provide graduates with skills in the chemistry and biology of cancer, and direct experience of some of the very latest research in the field.
The course will cover new approaches to cancer diagnosis and treatment and involve the design and synthesis of small molecule cancer drugs, equipping graduates for employment in the pharmaceutical industry and in academia.
The pioneering degree has been developed by Dr. Paul Jenkins from the Department of Chemistry, who has research expertise in the development of chemotherapeutic drugs.
He said “I think that this unique course will equip graduates to take part in the exciting and rewarding field of anti-cancer drug development. It will explain the biological pathways involved in cancer and how to design non-toxic small molecules to intervene specifically in these pathways to produce the next generation of cancer drugs.”
The main issue with cancer chemotherapy at the moment is that it is based on selective toxicity of the cancer drug for the tumour cells. This selectivity is never perfect and the treatments have considerable side effects.
One of the newest cancer drugs is Gleevec which is a specific non toxic inhibitor of a key protein in a cancer control pathway. Future developments will involve drugs of this type.
Leicester is a national centre for clinical research in the field of cancer. The Chemistry Department is conducting research funded by CRUK to develop non-toxic inhibitors of a key check-point enzyme in the cell division process.
In cancer cells, growth is very rapid and one way to combat this is to stop cells dividing by specific inhibition of the enzymes that control the cell cycle. “Our results have been encouraging” said Dr. Jenkins, “and two of our researchers will present results at a medicinal chemistry conference in Lille later this year.”
The degree is aimed at graduates in chemistry or a related discipline and non-graduates with appropriate experience. Cancer Research UK has supplied three bursaries covering fees and stipend for UK and EEA students taking the MSc in Cancer Chemistry.
Ather Mirza | alfa
NYSCF researchers develop novel bioengineering technique for personalized bone grafts
18.07.2018 | New York Stem Cell Foundation
Pollen taxi for bacteria
18.07.2018 | Technische Universität München
For the first time ever, scientists have determined the cosmic origin of highest-energy neutrinos. A research group led by IceCube scientist Elisa Resconi, spokesperson of the Collaborative Research Center SFB1258 at the Technical University of Munich (TUM), provides an important piece of evidence that the particles detected by the IceCube neutrino telescope at the South Pole originate from a galaxy four billion light-years away from Earth.
To rule out other origins with certainty, the team led by neutrino physicist Elisa Resconi from the Technical University of Munich and multi-wavelength...
For the first time a team of researchers have discovered two different phases of magnetic skyrmions in a single material. Physicists of the Technical Universities of Munich and Dresden and the University of Cologne can now better study and understand the properties of these magnetic structures, which are important for both basic research and applications.
Whirlpools are an everyday experience in a bath tub: When the water is drained a circular vortex is formed. Typically, such whirls are rather stable. Similar...
Physicists working with Roland Wester at the University of Innsbruck have investigated if and how chemical reactions can be influenced by targeted vibrational excitation of the reactants. They were able to demonstrate that excitation with a laser beam does not affect the efficiency of a chemical exchange reaction and that the excited molecular group acts only as a spectator in the reaction.
A frequently used reaction in organic chemistry is nucleophilic substitution. It plays, for example, an important role in in the synthesis of new chemical...
Optical spectroscopy allows investigating the energy structure and dynamic properties of complex quantum systems. Researchers from the University of Würzburg present two new approaches of coherent two-dimensional spectroscopy.
"Put an excitation into the system and observe how it evolves." According to physicist Professor Tobias Brixner, this is the credo of optical spectroscopy....
Ultra-short, high-intensity X-ray flashes open the door to the foundations of chemical reactions. Free-electron lasers generate these kinds of pulses, but there is a catch: the pulses vary in duration and energy. An international research team has now presented a solution: Using a ring of 16 detectors and a circularly polarized laser beam, they can determine both factors with attosecond accuracy.
Free-electron lasers (FELs) generate extremely short and intense X-ray flashes. Researchers can use these flashes to resolve structures with diameters on the...
13.07.2018 | Event News
12.07.2018 | Event News
03.07.2018 | Event News
18.07.2018 | Life Sciences
18.07.2018 | Materials Sciences
18.07.2018 | Health and Medicine