Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Scientists discover new virus caused deaths of transplant recipients from single donor

25.04.2007
Knowledge of genetic sequence of virus will enable improvements in screening to enhance transplantation safety

Scientists in the Greene Infectious Disease Laboratory of the Columbia University Mailman School of Public Health and colleagues in the Victorian Infectious Diseases Reference Laboratory in Melbourne, Australia and 454 Life Sciences have discovered a new virus that was responsible for the deaths of three transplant recipients who received organs from a single donor in Victoria, Australia.

The previously unknown virus, which is related to lymphocytic choreomeningitis virus (LCMV), was found using rapid sequencing technology established by 454 Life Sciences and bioinformatics algorithms developed in the Greene Laboratory with support from the National Institute of Allergy and Infectious Diseases. Known strains of LCMV have been implicated in a small number of cases of disease transmission by organ transplantation, however, the newly discovered virus is sufficiently different that it could not be detected using existing screening methods.

Over 30,000 organ transplants are performed in the U.S. each year. Knowledge of the genetic sequence of this virus will enable improvements in screening that will enhance the safety of transplantation.

... more about:
»Greene »Infectious »Laboratory »transplant

Ian Lipkin, MD, director of the Greene Laboratory and Principal Investigator of the Northeast Biodefense Center, emphasized the importance of academic, public health, and industrial partnership in this work. "This was a team effort. Drs. Mike Catton and Julian Druce at the Victorian Infectious Disease Reference Laboratory reached out to us after a comprehensive state-of-the-art investigation failed to turn up leads," stated Dr. Lipkin. "We succeeded in identifying the virus responsible for the deaths by building on their work and utilizing new tools for pathogen surveillance and discovery developed in the Greene Laboratory and 454 Life Sciences."

Randee Sacks Levine | EurekAlert!
Further information:
http://www.columbia.edu

Further reports about: Greene Infectious Laboratory transplant

More articles from Life Sciences:

nachricht A novel synthetic antibody enables conditional “protein knockdown” in vertebrates
20.08.2018 | Technische Universität Dresden

nachricht Climate Impact Research in Hannover: Small Plants against Large Waves
17.08.2018 | Leibniz Universität Hannover

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: It’s All in the Mix: Jülich Researchers are Developing Fast-Charging Solid-State Batteries

There are currently great hopes for solid-state batteries. They contain no liquid parts that could leak or catch fire. For this reason, they do not require cooling and are considered to be much safer, more reliable, and longer lasting than traditional lithium-ion batteries. Jülich scientists have now introduced a new concept that allows currents up to ten times greater during charging and discharging than previously described in the literature. The improvement was achieved by a “clever” choice of materials with a focus on consistently good compatibility. All components were made from phosphate compounds, which are well matched both chemically and mechanically.

The low current is considered one of the biggest hurdles in the development of solid-state batteries. It is the reason why the batteries take a relatively long...

Im Focus: Color effects from transparent 3D-printed nanostructures

New design tool automatically creates nanostructure 3D-print templates for user-given colors
Scientists present work at prestigious SIGGRAPH conference

Most of the objects we see are colored by pigments, but using pigments has disadvantages: such colors can fade, industrial pigments are often toxic, and...

Im Focus: Unraveling the nature of 'whistlers' from space in the lab

A new study sheds light on how ultralow frequency radio waves and plasmas interact

Scientists at the University of California, Los Angeles present new research on a curious cosmic phenomenon known as "whistlers" -- very low frequency packets...

Im Focus: New interactive machine learning tool makes car designs more aerodynamic

Scientists develop first tool to use machine learning methods to compute flow around interactively designable 3D objects. Tool will be presented at this year’s prestigious SIGGRAPH conference.

When engineers or designers want to test the aerodynamic properties of the newly designed shape of a car, airplane, or other object, they would normally model...

Im Focus: Robots as 'pump attendants': TU Graz develops robot-controlled rapid charging system for e-vehicles

Researchers from TU Graz and their industry partners have unveiled a world first: the prototype of a robot-controlled, high-speed combined charging system (CCS) for electric vehicles that enables series charging of cars in various parking positions.

Global demand for electric vehicles is forecast to rise sharply: by 2025, the number of new vehicle registrations is expected to reach 25 million per year....

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

LaserForum 2018 deals with 3D production of components

17.08.2018 | Event News

Within reach of the Universe

08.08.2018 | Event News

A journey through the history of microscopy – new exhibition opens at the MDC

27.07.2018 | Event News

 
Latest News

Quantum bugs, meet your new swatter

20.08.2018 | Information Technology

A novel synthetic antibody enables conditional “protein knockdown” in vertebrates

20.08.2018 | Life Sciences

Metamolds: Molding a mold

20.08.2018 | Information Technology

VideoLinks
Science & Research
Overview of more VideoLinks >>>