Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Thioethers synthesis process

03.04.2007
Although today there exists a number of methods for the synthesis of organic molecules (the main components of certain medicines, foods, additives, paints, fabrics, liquid crystals, etc.), in most cases toxic reagents and solvents have to be used.

In these processes, moreover, contaminant waste is produced This is why coming up with a procedure that avoids these drawbacks is a good thing all round. As regards solvents, water is undoubtedly the most suitable, in this respect, due to its abundance, utility, economy, non-toxicity and environmental advantages. And what about if the key to the reaction is using the minimum quantity of catalyst? And if all that involved in the reaction (including the catalyst) is recyclable or can be directly reused?

These precisely, have been the goals of a research group of the Department of Organic Chemistry II at the University of the Basque Country (UPV-EHU) on proposing a new method for the synthesis of diaryl sulphide, objectives which, to a great extent have been met. This is because, for the invention of a method for the synthesis of thioether derivatives, diaryl sulphides are prepared in a very simple way employing a catalyst of copper salt in water. This reaction medium is recyclable. Thus, it is worth studying in depth the research work undertaken by the UPV-EHU and which is patent- protected.

Diaryl sulphides are essential components in certain medicinal drugs and their structure or “skeleton” also appears in pharmacologically efficient molecules. In any case, their methods of synthesis are limited, given that, apart from the fact that they are not viable on applying them in great quantities, they are also quite contaminant. In fact, bonding arene and sulphur (the C(aryl)-S bond) has been no easy task, historically. With the process carried out by doctors M. Carril, R. San Martín and E. Domínguez, water is the only solvent employed in the reaction; it is a cheap solvent, easily handled and does not produce any contamination. Likewise, the initial reagents (arylthiols and halides) are accessible in great quantities. The catalyst sources, i.e. the copper salts are cheap and, as the reaction is produced in an aqueous medium, there is no need for any extreme condition such as an inert atmosphere. Once the reaction is concluded, the results are extracted from the aqueous medium where the catalyst is found and the reagents and base can be added to start the reaction again. As both the solvent and the copper source can be reused, the costs savings are evident. Also, the water, unlike many solvents used in industrial processes, is not toxic, nor is it flammable. Its safety behaviour is such that no safety measure is necessary for its storage or in its handling.

... more about:
»catalyst »solvent »sulphide »synthesis

In this respect, it would be desirable for this method for the sustainable development employed in the case of diaryl sulphide to be a reality for other chemical processes.

Irati Kortabitarte | alfa
Further information:
http://www.basqueresearch.com/berria_irakurri.asp?Gelaxka=1_1&hizk=I&Berri_Kod=1264

Further reports about: catalyst solvent sulphide synthesis

More articles from Life Sciences:

nachricht Scientists uncover the role of a protein in production & survival of myelin-forming cells
19.07.2018 | Advanced Science Research Center, GC/CUNY

nachricht NYSCF researchers develop novel bioengineering technique for personalized bone grafts
18.07.2018 | New York Stem Cell Foundation

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Future electronic components to be printed like newspapers

A new manufacturing technique uses a process similar to newspaper printing to form smoother and more flexible metals for making ultrafast electronic devices.

The low-cost process, developed by Purdue University researchers, combines tools already used in industry for manufacturing metals on a large scale, but uses...

Im Focus: First evidence on the source of extragalactic particles

For the first time ever, scientists have determined the cosmic origin of highest-energy neutrinos. A research group led by IceCube scientist Elisa Resconi, spokesperson of the Collaborative Research Center SFB1258 at the Technical University of Munich (TUM), provides an important piece of evidence that the particles detected by the IceCube neutrino telescope at the South Pole originate from a galaxy four billion light-years away from Earth.

To rule out other origins with certainty, the team led by neutrino physicist Elisa Resconi from the Technical University of Munich and multi-wavelength...

Im Focus: Magnetic vortices: Two independent magnetic skyrmion phases discovered in a single material

For the first time a team of researchers have discovered two different phases of magnetic skyrmions in a single material. Physicists of the Technical Universities of Munich and Dresden and the University of Cologne can now better study and understand the properties of these magnetic structures, which are important for both basic research and applications.

Whirlpools are an everyday experience in a bath tub: When the water is drained a circular vortex is formed. Typically, such whirls are rather stable. Similar...

Im Focus: Breaking the bond: To take part or not?

Physicists working with Roland Wester at the University of Innsbruck have investigated if and how chemical reactions can be influenced by targeted vibrational excitation of the reactants. They were able to demonstrate that excitation with a laser beam does not affect the efficiency of a chemical exchange reaction and that the excited molecular group acts only as a spectator in the reaction.

A frequently used reaction in organic chemistry is nucleophilic substitution. It plays, for example, an important role in in the synthesis of new chemical...

Im Focus: New 2D Spectroscopy Methods

Optical spectroscopy allows investigating the energy structure and dynamic properties of complex quantum systems. Researchers from the University of Würzburg present two new approaches of coherent two-dimensional spectroscopy.

"Put an excitation into the system and observe how it evolves." According to physicist Professor Tobias Brixner, this is the credo of optical spectroscopy....

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

Leading experts in Diabetes, Metabolism and Biomedical Engineering discuss Precision Medicine

13.07.2018 | Event News

Conference on Laser Polishing – LaP: Fine Tuning for Surfaces

12.07.2018 | Event News

11th European Wood-based Panel Symposium 2018: Meeting point for the wood-based materials industry

03.07.2018 | Event News

 
Latest News

A smart safe rechargeable zinc ion battery based on sol-gel transition electrolytes

20.07.2018 | Power and Electrical Engineering

Reversing cause and effect is no trouble for quantum computers

20.07.2018 | Information Technology

Princeton-UPenn research team finds physics treasure hidden in a wallpaper pattern

20.07.2018 | Materials Sciences

VideoLinks
Science & Research
Overview of more VideoLinks >>>