Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

A bitter pill for a sugar-coated killer

20.03.2007
Dr Fritz Mühlschlegel, a Reader at the Department of Biosciences, University of Kent, and Consultant Medical Microbiologist in the East Kent Hospitals Trust, has been awarded £400k by the Medical Research Council to combat fungal brain infection.

The fungus Cryptococcus neoformans can infect the human brain leading to disease (cryptococcosis) that is usually fatal if untreated. It is ‘dressed to kill’ with a sugar coat that protects it against attack by the human immune system. Dr Mühlschlegel will now conduct research into how the production of the fungal sugar coat is regulated. Previously his team discovered how elevated concentrations of carbon dioxide, found in the human body, influence the production of the fungal sugar coat. With this grant he can now investigate the molecular detail of this process.

Dr Mühlschlegel said: ‘Almost 40 million people worldwide are infected with HIV and more than 60% of these (approximately 25.8 million) live in sub-Saharan Africa. Cryptococcosis is the initial defining illness in 88% of AIDS patients in southern Africa. In addition to these HIV infected cases, we also see cryptococcal infection in immunosuppressed transplant patients.’

Professor Peter Jeffries, Dean of the Faculty of Science, Technology and Medical Sciences at the University of Kent said: ‘This is excellent news in that a better understanding of Cryptococcus neoformans may identify additional ways to diagnose and treat this important fungal infection.’

... more about:
»Medical »Mühlschlegel »coat »fungal

Ruth Lapworth, Clinical Director of Pathology in the East Kent Hospitals Trust said: ‘Pathology services already have very strong links with the Department of Biosciences and the Medical Research Council award will underline this further.’

Gary Hughes | alfa
Further information:
http://www.kent.ac.uk

Further reports about: Medical Mühlschlegel coat fungal

More articles from Life Sciences:

nachricht Researchers target protein that protects bacteria's DNA 'recipes'
21.08.2018 | University of Rochester

nachricht Protein interaction helps Yersinia cause disease
21.08.2018 | Schwedischer Forschungsrat - The Swedish Research Council

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: It’s All in the Mix: Jülich Researchers are Developing Fast-Charging Solid-State Batteries

There are currently great hopes for solid-state batteries. They contain no liquid parts that could leak or catch fire. For this reason, they do not require cooling and are considered to be much safer, more reliable, and longer lasting than traditional lithium-ion batteries. Jülich scientists have now introduced a new concept that allows currents up to ten times greater during charging and discharging than previously described in the literature. The improvement was achieved by a “clever” choice of materials with a focus on consistently good compatibility. All components were made from phosphate compounds, which are well matched both chemically and mechanically.

The low current is considered one of the biggest hurdles in the development of solid-state batteries. It is the reason why the batteries take a relatively long...

Im Focus: Color effects from transparent 3D-printed nanostructures

New design tool automatically creates nanostructure 3D-print templates for user-given colors
Scientists present work at prestigious SIGGRAPH conference

Most of the objects we see are colored by pigments, but using pigments has disadvantages: such colors can fade, industrial pigments are often toxic, and...

Im Focus: Unraveling the nature of 'whistlers' from space in the lab

A new study sheds light on how ultralow frequency radio waves and plasmas interact

Scientists at the University of California, Los Angeles present new research on a curious cosmic phenomenon known as "whistlers" -- very low frequency packets...

Im Focus: New interactive machine learning tool makes car designs more aerodynamic

Scientists develop first tool to use machine learning methods to compute flow around interactively designable 3D objects. Tool will be presented at this year’s prestigious SIGGRAPH conference.

When engineers or designers want to test the aerodynamic properties of the newly designed shape of a car, airplane, or other object, they would normally model...

Im Focus: Robots as 'pump attendants': TU Graz develops robot-controlled rapid charging system for e-vehicles

Researchers from TU Graz and their industry partners have unveiled a world first: the prototype of a robot-controlled, high-speed combined charging system (CCS) for electric vehicles that enables series charging of cars in various parking positions.

Global demand for electric vehicles is forecast to rise sharply: by 2025, the number of new vehicle registrations is expected to reach 25 million per year....

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

LaserForum 2018 deals with 3D production of components

17.08.2018 | Event News

Within reach of the Universe

08.08.2018 | Event News

A journey through the history of microscopy – new exhibition opens at the MDC

27.07.2018 | Event News

 
Latest News

Air pollution leads to cardiovascular diseases

21.08.2018 | Ecology, The Environment and Conservation

Researchers target protein that protects bacteria's DNA 'recipes'

21.08.2018 | Life Sciences

A paper battery powered by bacteria

21.08.2018 | Power and Electrical Engineering

VideoLinks
Science & Research
Overview of more VideoLinks >>>