Alternative yeast joins genome party.
Budding yeast Saccharomyces cerevisiae makes way for a new genome star.
First there was budding yeast (Saccharomyces cerevisiae). Partly responsible for scientists survival by fermenting their staples beer and bread, they polished off its DNA sequence back in 1997.
Now the minority fungus of lab culture - fission yeast (Schizosaccharomyces pombe) - is fighting back. This week S. pombe enters the experimental big leagues, with the announcement of its completed genome1.
Quality over quantity
S. pombes genome highlights the dissimilarity between the two yeasts. S. pombe has 4,824 genes - about 1,000 less than its cousin, and fewer even than some bacteria. This is evidence of quality over quantity, says Nurse, who led the sequencing effort.
Despite the yeasts differences, "its what they share thats important", says Nurse. He hopes that comparing the two genomes will reveal exactly which parts are essential for yeast life.
Nurses team has already compared the S. pombe genome to another five completed ones - those of budding yeast, the nematode worm Caenorhabditis elegans, the fruit fly (Drosophila), mustard weed (Arabidopsis thaliana) and humans - to find commonalities. All six organisms are eukaryotes - unlike bacteria, they package up their DNA and protein production into distinct compartments within the cell. The team identified a toolkit of some 60 genes that are essential for organizing and dividing eukaryotic cells.
Armed with the genome, S. pombe researchers hope to wade into its proteome, identifying all its proteins and how they interact. But once again, theyre playing catch-up - budding-yeast researchers are well on their way towards this goal.
Still, S. pombe scientists are used to struggling for recognition. And, despite a slow start and early rivalry, "no one would argue for only one yeast now", says Russell.
Scientists still harking after S. cervisiaes brewing power may be won over by S. pombes potential. First described by Swiss researcher Lindner in 1893, he isolated it from East African millet beer - and named it after the Swahili word for beer, pombe.
HELEN PEARSON | © Nature News Service
Scientists propose new theory on Alzheimer's, amyloid connection
23.04.2019 | Florida Atlantic University
Research on TGN1412 – Fc:Fcγ receptor interaction: Strong binding does not mean strong effect
23.04.2019 | Paul-Ehrlich-Institut - Bundesinstitut für Impfstoffe und biomedizinische Arzneimittel
Researchers led by Francesca Ferlaino from the University of Innsbruck and the Austrian Academy of Sciences report in Physical Review X on the observation of supersolid behavior in dipolar quantum gases of erbium and dysprosium. In the dysprosium gas these properties are unprecedentedly long-lived. This sets the stage for future investigations into the nature of this exotic phase of matter.
Supersolidity is a paradoxical state where the matter is both crystallized and superfluid. Predicted 50 years ago, such a counter-intuitive phase, featuring...
A stellar flare 10 times more powerful than anything seen on our sun has burst from an ultracool star almost the same size as Jupiter
A localization phenomenon boosts the accuracy of solving quantum many-body problems with quantum computers which are otherwise challenging for conventional computers. This brings such digital quantum simulation within reach on quantum devices available today.
Quantum computers promise to solve certain computational problems exponentially faster than any classical machine. “A particularly promising application is the...
The technology could revolutionize how information travels through data centers and artificial intelligence networks
Engineers at the University of California, Berkeley have built a new photonic switch that can control the direction of light passing through optical fibers...
Physicists observe how electron-hole pairs drift apart at ultrafast speed, but still remain strongly bound.
Modern electronics relies on ultrafast charge motion on ever shorter length scales. Physicists from Regensburg and Gothenburg have now succeeded in resolving a...
17.04.2019 | Event News
15.04.2019 | Event News
09.04.2019 | Event News
23.04.2019 | Life Sciences
23.04.2019 | Physics and Astronomy
18.04.2019 | Life Sciences