GENOPIA Biomedical LLC (GENOPIA), a biotechnology firm headquartered in Saarbücken, Germany and Ciphergen Biosystems, Inc. (Nasdaq: CIPH) in Fremont, CA, will collaborate on the discovery and the development of new drug targets and candidates for CNS diseases. GENOPIA Biomedical focuses on the development of novel drug candidates and uses advanced proteomics as its main drug discovery and high-throughput screening tool, while Ciphergen Biosystems is a world leader in the development of proteomics technology, most notably its SELDI (Surface-Enhanced Laser Desorption/Ionization) ProteinChip® technology. The close collaboration between GENOPIA and Ciphergen reflects the growing importance of proteomics in modern drug discovery. Plans include the joint development of highly customized ProteinChip® surfaces to meet GENOPIA ’s needs for its proprietary drug targets.
Drs. Bernhard Schu (CEO) and Helge Völkel (CSO) of GENOPIA , commented on the collaboration between the two companies: "Stroke is one of the most common neurological conditions, and represents one of the largest pharmaceutical markets in the 21st century. Scientists at GENOPIA have identified proteins that play key roles in the cellular response to hypoxia and hypoxia-reperfusion injury, key components of stroke. In a mouse model of stroke, we were able to demonstrate the importance of these target proteins. The use of specially adapted, state-of-the-art Ciphergen ProteinChip® technology will greatly accelerate our drug discovery process, and also allow us to shorten the time to further characterize our already identified drug candidates."
Drs. Bernhard Schu and Helge Voelkel continued "The objective is to accelerate protein biology research, with the same ease and success in which genomic and molecular biology research is done today. We envision new products that combine the expertise of both companies to create rapid ‘gene to protein’ transcription, translation, and protein purification capabilities at various scales, tagged or tag-free, as well as advanced ‘on-chip’ molecular-interaction and cellular assay platforms that further enable functional genomics."
Key evidence associating hydrophobicity with effective acid catalysis
25.03.2019 | Tokyo Metropolitan University
Bacteria may travel thousands of miles through the air globally
25.03.2019 | Rutgers University
DESY and MPSD scientists create high-order harmonics from solids with controlled polarization states, taking advantage of both crystal symmetry and attosecond electronic dynamics. The newly demonstrated technique might find intriguing applications in petahertz electronics and for spectroscopic studies of novel quantum materials.
The nonlinear process of high-order harmonic generation (HHG) in gases is one of the cornerstones of attosecond science (an attosecond is a billionth of a...
Nano- and microtechnology are promising candidates not only for medical applications such as drug delivery but also for the creation of little robots or flexible integrated sensors. Scientists from the Max Planck Institute for Polymer Research (MPI-P) have created magnetic microparticles, with a newly developed method, that could pave the way for building micro-motors or guiding drugs in the human body to a target, like a tumor. The preparation of such structures as well as their remote-control can be regulated using magnetic fields and therefore can find application in an array of domains.
The magnetic properties of a material control how this material responds to the presence of a magnetic field. Iron oxide is the main component of rust but also...
Due to the special arrangement of its molecules, a new coating made of corn starch is able to repair small scratches by itself through heat: The cross-linking via ring-shaped molecules makes the material mobile, so that it compensates for the scratches and these disappear again.
Superficial micro-scratches on the car body or on other high-gloss surfaces are harmless, but annoying. Especially in the luxury segment such surfaces are...
The Potsdam Echelle Polarimetric and Spectroscopic Instrument (PEPSI) at the Large Binocular Telescope (LBT) in Arizona released its first image of the surface magnetic field of another star. In a paper in the European journal Astronomy & Astrophysics, the PEPSI team presents a Zeeman- Doppler-Image of the surface of the magnetically active star II Pegasi.
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Researchers at Chalmers University of Technology and the University of Gothenburg, Sweden, have proposed a way to create a completely new source of radiation. Ultra-intense light pulses consist of the motion of a single wave and can be described as a tsunami of light. The strong wave can be used to study interactions between matter and light in a unique way. Their research is now published in the scientific journal Physical Review Letters.
"This source of radiation lets us look at reality through a new angle - it is like twisting a mirror and discovering something completely different," says...
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25.03.2019 | Life Sciences
25.03.2019 | Life Sciences
25.03.2019 | Life Sciences