The MRC Council has approved a recommendation from its Physiological Systems and Clinical Sciences Board to provide an increased budget of £14.9 million over the five year period April 2007-2012.
The Unit received funding of £7.5 million for the period 2002-2007.
After a rigorous review which involved seeking the opinions of 30 international experts in the field, the MRC Council gave the highest possible 6.0 rating for the Unit's recent work and future proposals.
The Council also approved the appointment of Professor Dario Alessi as Deputy Director of the Unit.
"This major new commitment from the MRC to the Unit in Dundee is a tremendous boost, and recognises the pre-eminence we have achieved in this field worldwide," said Professor Sir Philip Cohen, Director of the MRC Protein Phosphorylation Unit.
"The additional funding will allow us to expand our cutting-edge research programmes - which aim to understand the causes of global diseases such as arthritis, cancer, diabetes, hypertension and Parkinson's - and to use this information to facilitate the development of drugs to treat these conditions in partnership with the six major pharmaceutical companies with whom we collaborate."
When the new positions awarded are filled, the MRC Protein Phosphorylation Unit will have nine Programme Leaders and 115 staff and account for 16% of the on-going research in the College of Life Sciences at Dundee.
Over the past five years some of the highlights of the Unit's research have included the explanation of how a tumour suppressor called LKB1 prevents cancers from forming, the validation of the enzyme PDK1 as a key target for the development of an anti-cancer drug, the discovery of why mutations in an enzyme called WNK1 cause an inherited hypertension syndrome and the identification of new drug targets to treat chronic inflammatory diseases.
The MRC Council also announced that Dr Nick Morrice, Head of Proteomics in the Unit would be promoted from Band 3 to Band 2 and Dr Kei Sakamoto, Head of the Unit's Molecular Physiology Laboratory from Band 4 to Band 3, both effective April 2007.
The Council also gave approval for the Unit to recruit a biologically-focused Programme Leader with significant X-ray crystallographic expertise, a position which has just been advertised.
Roddy Isles | alfa
Mass spectrometry sheds new light on thallium poisoning cold case
14.12.2018 | University of Maryland
Protein involved in nematode stress response identified
14.12.2018 | University of Illinois College of Agricultural, Consumer and Environmental Sciences
The more objects we make "smart," from watches to entire buildings, the greater the need for these devices to store and retrieve massive amounts of data quickly without consuming too much power.
Millions of new memory cells could be part of a computer chip and provide that speed and energy savings, thanks to the discovery of a previously unobserved...
What if, instead of turning up the thermostat, you could warm up with high-tech, flexible patches sewn into your clothes - while significantly reducing your...
A widely used diabetes medication combined with an antihypertensive drug specifically inhibits tumor growth – this was discovered by researchers from the University of Basel’s Biozentrum two years ago. In a follow-up study, recently published in “Cell Reports”, the scientists report that this drug cocktail induces cancer cell death by switching off their energy supply.
The widely used anti-diabetes drug metformin not only reduces blood sugar but also has an anti-cancer effect. However, the metformin dose commonly used in the...
A research team from the University of Zurich has developed a new drone that can retract its propeller arms in flight and make itself small to fit through narrow gaps and holes. This is particularly useful when searching for victims of natural disasters.
Inspecting a damaged building after an earthquake or during a fire is exactly the kind of job that human rescuers would like drones to do for them. A flying...
Over the last decade, there has been much excitement about the discovery, recognised by the Nobel Prize in Physics only two years ago, that there are two types...
12.12.2018 | Event News
10.12.2018 | Event News
06.12.2018 | Event News
14.12.2018 | Power and Electrical Engineering
14.12.2018 | Physics and Astronomy
14.12.2018 | Physics and Astronomy