Chemistry teams from two universities – Lomonosov Moscow State University and Texas A&M University (USA) have improved the efficacy of pharmaceutical substance synthesis by simplifying the process. The Russian team is guided by Academician Irina Beletskaya, and the US team by Professor David Edward Bergbreiter. These two teams play on the same side because the nanoreactor concept they are using will in the long run allow to simplify in many respects chemical and pharmaceutical technology and, most importantly, to make it cleaner from the ecological point of view. The research has been sponsored by the CRDF foundation and the Federal Agency for Science and Innovation (Rosnauka).
Synthesis of biologically active molecules, such as pharmaceutical drugs, is connected with a number of complications. It is easy on paper to “assemble” chains of various atoms into required structures, but in nature, enzymes – natural catalysts – help to synthesize these substances. The synthesis can not be performed without catalysts in the laboratory and, accordingly, in the industry.
In live systems, catalysts are a natural part of these systems, which have been perfected over millions of years of evolution, to the minutest detail. However in the human body, even the best of known catalysts, such as platinum metals and palladium suffer from at least two drawbacks.
Sergey Komarov | alfa
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