The circulation of cancer cells through the blood vessels is often the cause of metastasis. These cancer cells contaminate normal cells and the pathology spreads throughout the body. Metastasis is the main risk in cancers. In order to prevent this process from occurring, a team from the Chemistry Faculty at the Donostia-San Sebastián campus of the University of the Basque Country (UPV-EHU) analysed the connections between cancer and normal cells.
Concretely, the UPV-EHU analysed the proteins that are involved in these connections. From amongst these proteins, they chose the ones that have a single active centre. If this centre is blocked, the cancer cell will not be able to adhere itself to a healthy cell and, thus, this path of spreading the disease is blocked.
The first thing to do is to analyse the structure of the proteins chosen. This task is undertaken using computers, given that the proteins are gigantic molecules. Once the structure is analysed and with the data for the active centre of the connection, the design of a new, small molecule to block this centre is initiated.
Garazi Andonegi | alfa
Fish recognize their prey by electric colors
13.11.2018 | Rheinische Friedrich-Wilhelms-Universität Bonn
The dawn of a new era for genebanks - molecular characterisation of an entire genebank collection
13.11.2018 | Leibniz-Institut für Pflanzengenetik und Kulturpflanzenforschung
Biochips have been developed at TU Wien (Vienna), on which tissue can be produced and examined. This allows supplying the tissue with different substances in a very controlled way.
Cultivating human cells in the Petri dish is not a big challenge today. Producing artificial tissue, however, permeated by fine blood vessels, is a much more...
Faster and secure data communication: This is the goal of a new joint project involving physicists from the University of Würzburg. The German Federal Ministry of Education and Research funds the project with 14.8 million euro.
In our digital world data security and secure communication are becoming more and more important. Quantum communication is a promising approach to achieve...
On Saturday, 10 November 2018, the research icebreaker Polarstern will leave its homeport of Bremerhaven, bound for Cape Town, South Africa.
When choosing materials to make something, trade-offs need to be made between a host of properties, such as thickness, stiffness and weight. Depending on the application in question, finding just the right balance is the difference between success and failure
Now, a team of Penn Engineers has demonstrated a new material they call "nanocardboard," an ultrathin equivalent of corrugated paper cardboard. A square...
Physicists at ETH Zurich demonstrate how errors that occur during the manipulation of quantum system can be monitored and corrected on the fly
The field of quantum computation has seen tremendous progress in recent years. Bit by bit, quantum devices start to challenge conventional computers, at least...
09.11.2018 | Event News
06.11.2018 | Event News
23.10.2018 | Event News
13.11.2018 | Life Sciences
13.11.2018 | Life Sciences
13.11.2018 | Awards Funding