"You can eat your relatives but not your friends," could be the off-kilter credo of a tiny marine invertebrate called a sea squirt that can physically merge with, and parasitize, its own kin. The trigger for this unseemly behavior has now been traced to a single gene, isolated by researchers at the Stanford University School of Medicine. That gene also points to a common origin with the vertebrate immune system, far back in animal evolution, potentially shedding light on the development of our own immune system.
The sea squirt with the questionable philosophy is Botryllus schlosseri, a colonial animal that looks deceptively like a small flower. Each of its apparent petals is actually a separate, though genetically identical, organism, linked to the others by a common blood vessel. Ringing the tiny petals are even tinier tentacle-like ampullae, the sensing organs that evaluate other sea squirts, determining whos related and who isnt.
If two adjacent squirts arent related, their respective ampullae blacken and shrivel upon contact. But when the squirts are related, they begin to physically fuse together. Thus, the ampullae had to be able to sense genetic similarity among sea squirts, said Anthony De Tomaso, PhD, researcher in pathology and first author of a paper on the subject in the Nov. 24 issue of Nature. "We were looking for the genes which control how an individual can distinguish self from non-self," he said.
Magic number colloidal clusters
13.12.2018 | Friedrich-Alexander-Universität Erlangen-Nürnberg
Record levels of mercury released by thawing permafrost in Canadian Arctic
13.12.2018 | University of Alberta
What if, instead of turning up the thermostat, you could warm up with high-tech, flexible patches sewn into your clothes - while significantly reducing your...
A widely used diabetes medication combined with an antihypertensive drug specifically inhibits tumor growth – this was discovered by researchers from the University of Basel’s Biozentrum two years ago. In a follow-up study, recently published in “Cell Reports”, the scientists report that this drug cocktail induces cancer cell death by switching off their energy supply.
The widely used anti-diabetes drug metformin not only reduces blood sugar but also has an anti-cancer effect. However, the metformin dose commonly used in the...
A research team from the University of Zurich has developed a new drone that can retract its propeller arms in flight and make itself small to fit through narrow gaps and holes. This is particularly useful when searching for victims of natural disasters.
Inspecting a damaged building after an earthquake or during a fire is exactly the kind of job that human rescuers would like drones to do for them. A flying...
Over the last decade, there has been much excitement about the discovery, recognised by the Nobel Prize in Physics only two years ago, that there are two types...
What if a sensor sensing a thing could be part of the thing itself? Rice University engineers believe they have a two-dimensional solution to do just that.
Rice engineers led by materials scientists Pulickel Ajayan and Jun Lou have developed a method to make atom-flat sensors that seamlessly integrate with devices...
12.12.2018 | Event News
10.12.2018 | Event News
06.12.2018 | Event News
13.12.2018 | Life Sciences
13.12.2018 | Physics and Astronomy
13.12.2018 | Earth Sciences