Findings may help elucidate mechanisms of wake-sleep transitions and epileptic seizures
Astrocytes, a non-neuronal cell of the brain, are responsible for coordinating neuronal networks. Courtesy of Olivier Pascual and Philip Haydon, University of Pennsylvania School of Medicine, Department of Neuroscience
Researchers at the University of Pennsylvania School of Medicine have demonstrated that star-shaped glial cells in the brain called astrocytes are directly involved in regulating communication between neurons. A central finding of the study is that astrocytes modulate the level of a signaling molecule called adenosine, which is thought to be important in controlling wake-to-sleep transitions and epileptic seizures.
"This finding may cause neuroscientists to radically alter their view of the role of astrocytes as merely supportive to one of actively communicating with and instructing neurons," states senior author Philip G. Haydon, PhD, Professor of Neuroscience. "Astrocytes are not just the kitchen cells of the brain, providing nutritional support, but instead also help the neurons talk to each other." Haydon and colleagues published their results in last weeks issue of Science.
Karen Kreeger | EurekAlert!
Gut microbiome regulates the intestinal immune system, researchers find
19.12.2018 | Brown University
Greener days ahead for carbon fuels
19.12.2018 | DOE/Lawrence Berkeley National Laboratory
Different eras of civilization are defined by the discovery of new materials, as new materials drive new capabilities. And yet, identifying the best material...
Researchers from the University of Basel have reported a new method that allows the physical state of just a few atoms or molecules within a network to be controlled. It is based on the spontaneous self-organization of molecules into extensive networks with pores about one nanometer in size. In the journal ‘small’, the physicists reported on their investigations, which could be of particular importance for the development of new storage devices.
Around the world, researchers are attempting to shrink data storage devices to achieve as large a storage capacity in as small a space as possible. In almost...
The more objects we make "smart," from watches to entire buildings, the greater the need for these devices to store and retrieve massive amounts of data quickly without consuming too much power.
Millions of new memory cells could be part of a computer chip and provide that speed and energy savings, thanks to the discovery of a previously unobserved...
What if, instead of turning up the thermostat, you could warm up with high-tech, flexible patches sewn into your clothes - while significantly reducing your...
A widely used diabetes medication combined with an antihypertensive drug specifically inhibits tumor growth – this was discovered by researchers from the University of Basel’s Biozentrum two years ago. In a follow-up study, recently published in “Cell Reports”, the scientists report that this drug cocktail induces cancer cell death by switching off their energy supply.
The widely used anti-diabetes drug metformin not only reduces blood sugar but also has an anti-cancer effect. However, the metformin dose commonly used in the...
12.12.2018 | Event News
10.12.2018 | Event News
06.12.2018 | Event News
19.12.2018 | Materials Sciences
19.12.2018 | Materials Sciences
19.12.2018 | Life Sciences