Currently, the best way to predict whether a breast cancer is likely to recur is to determine whether tumor cells have invaded the lymph nodes near the breast. But new research from the Stanford University School of Medicine suggests that looking at the immune cells in those lymph nodes - instead of the tumor cells - will yield a more accurate forecast. The finding could help clinicians determine which cancers to treat more aggressively to ensure the cancer goes away and doesnt come back.
"Immune changes in the lymph node almost perfectly predict clinical outcome, much better than any other prognostic factor that is available today," said Peter P. Lee, MD, assistant professor of medicine and the senior author of the paper detailing the findings in the Sept. 6 advance online edition of Public Library of Science-Medicine.
In samples of breast cancer patients lymph nodes, Lee and his colleagues identified unique patterns of immune cells. When the researchers compared the immune profiles to whether a patients cancer returned within five years, they could divide the patients into two groups. The group with what Lee termed a "favorable" immune profile had an 85 to 90 percent chance of being disease-free after five years. The group with an "unfavorable" immune profile had less than a 15 percent chance.
Mitzi Baker | EurekAlert!
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In a recent publication in the renowned journal Optica, scientists of Leibniz-Institute of Photonic Technology (Leibniz IPHT) in Jena showed that they can accurately control the optical properties of liquid-core fiber lasers and therefore their spectral band width by temperature and pressure tuning.
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Scientists from the University of Freiburg and the University of Basel identified a master regulator for bone regeneration. Prasad Shastri, Professor of...
Moving into its fourth decade, AchemAsia is setting out for new horizons: The International Expo and Innovation Forum for Sustainable Chemical Production will take place from 21-23 May 2019 in Shanghai, China. With an updated event profile, the eleventh edition focusses on topics that are especially relevant for the Chinese process industry, putting a strong emphasis on sustainability and innovation.
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The BMBF-funded OWICELLS project was successfully completed with a final presentation at the BMW plant in Munich. The presentation demonstrated a Li-Fi communication with a mobile robot, while the robot carried out usual production processes (welding, moving and testing parts) in a 5x5m² production cell. The robust, optical wireless transmission is based on spatial diversity; in other words, data is sent and received simultaneously by several LEDs and several photodiodes. The system can transmit data at more than 100 Mbit/s and five milliseconds latency.
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An international team of scientists has discovered a new way to transfer image information through multimodal fibers with almost no distortion - even if the fiber is bent. The results of the study, to which scientist from the Leibniz-Institute of Photonic Technology Jena (Leibniz IPHT) contributed, were published on 6thJune in the highly-cited journal Physical Review Letters.
Endoscopes allow doctors to see into a patient’s body like through a keyhole. Typically, the images are transmitted via a bundle of several hundreds of optical...
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