The European Bioinformatics Institute and Flanders Interuniversity Institute for Biotechnology (VIB)–Ghent University have launched the PRoteomics IDEntifications database (PRIDE; www.ebi.ac.uk/pride). PRIDE allows researchers who work in the field of proteomics – the large-scale study of proteins – to share information much more readily than was previously possible. This will allow them to exploit the growing mass of information on how the body’s complement of proteins is altered in many disease states, paving the way towards new predictive and diagnostic methods in medicine.
Proteomics is the identification and characterization of all the proteins produced by a particular type of cell, tissue or organism under certain conditions. While an individual’s genome remains the same from one moment to the next, proteomes are extremely dynamic. For example, the set of proteins produced by your liver will change in response to eating a meal, and a healthy liver produces a different set of proteins than a diseased liver. Proteomics therefore has great potential, not only for helping us to understand how our environment affects the healthy body, but also for understanding disease mechanisms and developing new ways of diagnosing disease. Large international efforts to document all the proteins produced by several tissues, including liver, brain and blood plasma, are now underway. But although the high-throughput identification of proteins is gathering momentum, until recently there was no straightforward means of sharing or comparing the results.
“Proteomics labs were publishing their protein identifications,” explains Henning Hermjakob, leader of the EBI’s Proteomics Services Team, “but they had no guidelines as what information should be captured or how the information should be formatted. The proteomics community rapidly realized that researchers would only be able to exploit the results of their endeavours if they had a central repository that would allow them to make their results publicly available using agreed data standards.”
Sarah Sherwood | alfa
Breakthrough in designing a better Salmonella vaccine
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Proof of Concept: Gene therapy for mitochondrial diseases
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The Fraunhofer FEP has been involved in developing processes and equipment for cleaning, sterilization, and surface modification for decades. The CleanHand Network for development of systems and technologies to clean surfaces, materials, and objects was established in May 2018 to bundle the expertise of many partnering organizations. As a partner in the CleanHand Network, Fraunhofer FEP will present the Network and current research topics of the Institute in the field of hygiene and cleaning at the parts2clean trade fair, October 23-25, 2018 in Stuttgart, at the booth of the Fraunhofer Cleaning Technology Alliance (Hall 5, Booth C31).
Test reports and studies on the cleanliness of European motorway rest areas, hotel beds, and outdoor pools increasingly appear in the press, especially during...
The building blocks of matter in our universe were formed in the first 10 microseconds of its existence, according to the currently accepted scientific picture. After the Big Bang about 13.7 billion years ago, matter consisted mainly of quarks and gluons, two types of elementary particles whose interactions are governed by quantum chromodynamics (QCD), the theory of strong interaction. In the early universe, these particles moved (nearly) freely in a quark-gluon plasma.
This is a joint press release of University Muenster and Heidelberg as well as the GSI Helmholtzzentrum für Schwerionenforschung in Darmstadt.
Then, in a phase transition, they combined and formed hadrons, among them the building blocks of atomic nuclei, protons and neutrons. In the current issue of...
Thin-film solar cells made of crystalline silicon are inexpensive and achieve efficiencies of a good 14 percent. However, they could do even better if their shiny surfaces reflected less light. A team led by Prof. Christiane Becker from the Helmholtz-Zentrum Berlin (HZB) has now patented a sophisticated new solution to this problem.
"It is not enough simply to bring more light into the cell," says Christiane Becker. Such surface structures can even ultimately reduce the efficiency by...
A study in the journal Bulletin of Marine Science describes a new, blood-red species of octocoral found in Panama. The species in the genus Thesea was discovered in the threatened low-light reef environment on Hannibal Bank, 60 kilometers off mainland Pacific Panama, by researchers at the Smithsonian Tropical Research Institute in Panama (STRI) and the Centro de Investigación en Ciencias del Mar y Limnología (CIMAR) at the University of Costa Rica.
Scientists established the new species, Thesea dalioi, by comparing its physical traits, such as branch thickness and the bright red colony color, with the...
Scientists have succeeded in observing the first long-distance transfer of information in a magnetic group of materials known as antiferromagnets.
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25.09.2018 | Information Technology
25.09.2018 | Earth Sciences
25.09.2018 | Materials Sciences