A forthcoming paper in the international, open-access journal PLoS Medicine makes the strongest association yet between a newly identified virus and the pediatric respiratory disease commonly known as croup. Following their recent description of the coronavirus HCoV-NL63, Lia van der Hoek and colleagues suggest this is one of the most frequently detected viruses in children with lower respiratory tract infections (LRTIs). These infections are estimated by the World Health Organization to be responsible for one fifth of all deaths in children under five years old.
The team, including researchers from University Medical Centres in Amsterdam, Bochum and Freiberg, determined the incidence of this novel virus in a sample of children under three years old with such respiratory infections. Nine hundred and forty nine samples of nasopharyngeal secretions were collected from both hospitalized patients and outpatients in four different regions of Germany. The study found that forty-nine samples (5.2%) were positive for the virus HCoV-NL63 overall, with a greater incidence in outpatients (7.9%) than hospitalized patients (3.2%). Co-infection with two other viruses also known to be prominent in the cause of LRTIs, was also frequently observed.
The researchers also investigated the occurrence of HCoV-NL63 in cases of respiratory disease where no other virus could be detected. Here, a strong relationship with the clinical symptoms associated with croup was apparent: 43% of the HCoV-NL63 positive patients with high HCoV-NL63 load and absence of co-infection had croup, compared with 6% of HCoV-NL63 negative patients. Previous studies have reported trends in croup, such as the relative susceptibility of boys to the disease, its peak occurrence in the second year of life and its predominance in late autumn and earlier winter, that are matched by patterns of HCoV-NL63 occurrence.
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13.07.2018 | Max-Planck-Institut für Stoffwechselforschung
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13.07.2018 | Julius-Maximilians-Universität Würzburg
For the first time ever, scientists have determined the cosmic origin of highest-energy neutrinos. A research group led by IceCube scientist Elisa Resconi, spokesperson of the Collaborative Research Center SFB1258 at the Technical University of Munich (TUM), provides an important piece of evidence that the particles detected by the IceCube neutrino telescope at the South Pole originate from a galaxy four billion light-years away from Earth.
To rule out other origins with certainty, the team led by neutrino physicist Elisa Resconi from the Technical University of Munich and multi-wavelength...
For the first time a team of researchers have discovered two different phases of magnetic skyrmions in a single material. Physicists of the Technical Universities of Munich and Dresden and the University of Cologne can now better study and understand the properties of these magnetic structures, which are important for both basic research and applications.
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Physicists working with Roland Wester at the University of Innsbruck have investigated if and how chemical reactions can be influenced by targeted vibrational excitation of the reactants. They were able to demonstrate that excitation with a laser beam does not affect the efficiency of a chemical exchange reaction and that the excited molecular group acts only as a spectator in the reaction.
A frequently used reaction in organic chemistry is nucleophilic substitution. It plays, for example, an important role in in the synthesis of new chemical...
Optical spectroscopy allows investigating the energy structure and dynamic properties of complex quantum systems. Researchers from the University of Würzburg present two new approaches of coherent two-dimensional spectroscopy.
"Put an excitation into the system and observe how it evolves." According to physicist Professor Tobias Brixner, this is the credo of optical spectroscopy....
Ultra-short, high-intensity X-ray flashes open the door to the foundations of chemical reactions. Free-electron lasers generate these kinds of pulses, but there is a catch: the pulses vary in duration and energy. An international research team has now presented a solution: Using a ring of 16 detectors and a circularly polarized laser beam, they can determine both factors with attosecond accuracy.
Free-electron lasers (FELs) generate extremely short and intense X-ray flashes. Researchers can use these flashes to resolve structures with diameters on the...
13.07.2018 | Event News
12.07.2018 | Event News
03.07.2018 | Event News
13.07.2018 | Event News
13.07.2018 | Materials Sciences
13.07.2018 | Life Sciences