University of Michigan researchers have figured out one more component in cancer cells’ aggressive growth---and hope that knowledge can help kill the cells.
In the July issue of Cancer Cell, the scientists explain how cancer tumor cells attach themselves to a protein on the surface of cells lining blood vessel walls. When this attachment happens, it tells the cancer cell to grow and develop blood vessels, which feed the cell. Cun-Yu Wang, senior author on the paper, said this discovery could help in the fight against cancer. "The blood supply is key for tumor growth and tumor development," said Wang, the Richard H. Kingery Endowed Collegiate Professor at the U-M School of Dentistry. "If you cut off the blood supply, you stop cancer development."
Wang collaborated with researchers Qinghua Zeng, Shenglin Li, Douglas B. Chepeha, Jong Li, Honglai Zhang, Peter J. Polverini, Jacques Nor and Jan Kitajewski on the paper. Scientists have heavily studied cancer cells’ secretion of proteins to form blood vessels. But Wang said when researchers tried to turn off that process, some tumors responded and some did not, which left him curious about how to develop a better treatment.
Staying in Shape
16.08.2018 | Max-Planck-Institut für molekulare Zellbiologie und Genetik
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16.08.2018 | Okinawa Institute of Science and Technology (OIST) Graduate University
Scientists at the University of California, Los Angeles present new research on a curious cosmic phenomenon known as "whistlers" -- very low frequency packets...
Scientists develop first tool to use machine learning methods to compute flow around interactively designable 3D objects. Tool will be presented at this year’s prestigious SIGGRAPH conference.
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Researchers from TU Graz and their industry partners have unveiled a world first: the prototype of a robot-controlled, high-speed combined charging system (CCS) for electric vehicles that enables series charging of cars in various parking positions.
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Proteins must be folded correctly to fulfill their molecular functions in cells. Molecular assistants called chaperones help proteins exploit their inbuilt folding potential and reach the correct three-dimensional structure. Researchers at the Max Planck Institute of Biochemistry (MPIB) have demonstrated that actin, the most abundant protein in higher developed cells, does not have the inbuilt potential to fold and instead requires special assistance to fold into its active state. The chaperone TRiC uses a previously undescribed mechanism to perform actin folding. The study was recently published in the journal Cell.
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Scientists have discovered that the electrical resistance of a copper-oxide compound depends on the magnetic field in a very unusual way -- a finding that could help direct the search for materials that can perfectly conduct electricity at room temperatur
What happens when really powerful magnets--capable of producing magnetic fields nearly two million times stronger than Earth's--are applied to materials that...
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16.08.2018 | Life Sciences