Researchers have located a gene dubbed dead end that when mutated or lost, causes testicular tumors in mice. They say their study, published in the online journal Nature, on May 18, 2005 will likely offer future insights into the genetic causes of the disease in humans because the cancer originates from the same cell type, the primordial germ cell, in both mice and men.
If that notion is validated through further research, the finding could lead to a way to either screen for the human disease or treat it, say the researchers, who represent The University of Texas M. D. Anderson Cancer Center, Case Western Reserve University, Duke University Medical Center, the National Cancer Institute and the Lawrence Berkeley National Laboratory.
"One can envision that this gene or others in its pathway could possibly be used for screening or therapeutic purposes in young males predisposed to develop testicular cancer or those who have a family history of this disease," says the lead investigator, Angabin Matin, Ph.D., an assistant professor in the Department of Molecular Genetics at M. D. Anderson. "This will of course require further research regarding the function of this gene in human cancers."
Nancy Jensen | EurekAlert!
Microscope measures muscle weakness
16.11.2018 | Friedrich-Alexander-Universität Erlangen-Nürnberg
Good preparation is half the digestion
16.11.2018 | Max-Planck-Institut für Stoffwechselforschung
Researchers at the University of New Hampshire have captured a difficult-to-view singular event involving "magnetic reconnection"--the process by which sparse particles and energy around Earth collide producing a quick but mighty explosion--in the Earth's magnetotail, the magnetic environment that trails behind the planet.
Magnetic reconnection has remained a bit of a mystery to scientists. They know it exists and have documented the effects that the energy explosions can...
Biochips have been developed at TU Wien (Vienna), on which tissue can be produced and examined. This allows supplying the tissue with different substances in a very controlled way.
Cultivating human cells in the Petri dish is not a big challenge today. Producing artificial tissue, however, permeated by fine blood vessels, is a much more...
Faster and secure data communication: This is the goal of a new joint project involving physicists from the University of Würzburg. The German Federal Ministry of Education and Research funds the project with 14.8 million euro.
In our digital world data security and secure communication are becoming more and more important. Quantum communication is a promising approach to achieve...
On Saturday, 10 November 2018, the research icebreaker Polarstern will leave its homeport of Bremerhaven, bound for Cape Town, South Africa.
When choosing materials to make something, trade-offs need to be made between a host of properties, such as thickness, stiffness and weight. Depending on the application in question, finding just the right balance is the difference between success and failure
Now, a team of Penn Engineers has demonstrated a new material they call "nanocardboard," an ultrathin equivalent of corrugated paper cardboard. A square...
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16.11.2018 | Health and Medicine
16.11.2018 | Life Sciences
16.11.2018 | Life Sciences