Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Project could lead to anthrax drugs

18.04.2005


A project launched at the University of Essex could lead to the development of drugs capable of reversing the effects of the anthrax bacteria.



Dr Metodi Metodiev has been awarded almost £62,500 by the National Institute of Health, USA, to investigate the deadly effects of the anthrax bacteria on human cells.

The aim is to create a screening platform by which scientists can select ’inhibitors’ capable of stopping the progress of anthrax.


Dr Metodiev said: ’Anthrax kills human cells by invading them and binding to proteins vital for specific signal transduction pathways, the signalling process by which the cell communicates with the environment and with other cells. By interrupting that signalling pathway, anthrax kills the cell and eventually the patient.’

Yeast will be used to create ’yeast cells’ with the same signalling abilities of a human cell. These will be grown in a variety of different conditions replicating the effects of anthrax, and the signalling abilities will be monitored in the presence of different test compounds.

Dr Metodiev explained the advantages of using yeast: ’It allows us to screen potential therapeutics by genetic selection. As well, ’yeast cells’ can be grown quickly which is hugely beneficial because, if anthrax were used as a bio-weapon, it is likely to have been engineered and could therefore be resistant to existing drugs. By using yeast, we may be able to subject our imitation human cells to a number of different scenarios and identify and counteract the effect of the anthrax bacteria within days.’

The project is scheduled to last for two years but Dr Metodiev hopes to extend the project by a further five years depending on the outcomes of this stage.

Kate Clayton | alfa
Further information:
http://www.essex.ac.uk/wyvern

More articles from Life Sciences:

nachricht Insect Antibiotic Provides New Way to Eliminate Bacteria
15.11.2018 | Universität Zürich

nachricht New findings help to better calculate the oceans’ contribution to climate regulation
15.11.2018 | Jacobs University Bremen gGmbH

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: A Chip with Blood Vessels

Biochips have been developed at TU Wien (Vienna), on which tissue can be produced and examined. This allows supplying the tissue with different substances in a very controlled way.

Cultivating human cells in the Petri dish is not a big challenge today. Producing artificial tissue, however, permeated by fine blood vessels, is a much more...

Im Focus: A Leap Into Quantum Technology

Faster and secure data communication: This is the goal of a new joint project involving physicists from the University of Würzburg. The German Federal Ministry of Education and Research funds the project with 14.8 million euro.

In our digital world data security and secure communication are becoming more and more important. Quantum communication is a promising approach to achieve...

Im Focus: Research icebreaker Polarstern begins the Antarctic season

What does it look like below the ice shelf of the calved massive iceberg A68?

On Saturday, 10 November 2018, the research icebreaker Polarstern will leave its homeport of Bremerhaven, bound for Cape Town, South Africa.

Im Focus: Penn engineers develop ultrathin, ultralight 'nanocardboard'

When choosing materials to make something, trade-offs need to be made between a host of properties, such as thickness, stiffness and weight. Depending on the application in question, finding just the right balance is the difference between success and failure

Now, a team of Penn Engineers has demonstrated a new material they call "nanocardboard," an ultrathin equivalent of corrugated paper cardboard. A square...

Im Focus: Coping with errors in the quantum age

Physicists at ETH Zurich demonstrate how errors that occur during the manipulation of quantum system can be monitored and corrected on the fly

The field of quantum computation has seen tremendous progress in recent years. Bit by bit, quantum devices start to challenge conventional computers, at least...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

“3rd Conference on Laser Polishing – LaP 2018” Attracts International Experts and Users

09.11.2018 | Event News

On the brain’s ability to find the right direction

06.11.2018 | Event News

European Space Talks: Weltraumschrott – eine Gefahr für die Gesellschaft?

23.10.2018 | Event News

 
Latest News

Putting food-safety detection in the hands of consumers

15.11.2018 | Information Technology

Insect Antibiotic Provides New Way to Eliminate Bacteria

15.11.2018 | Life Sciences

New findings help to better calculate the oceans’ contribution to climate regulation

15.11.2018 | Life Sciences

VideoLinks
Science & Research
Overview of more VideoLinks >>>