Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

A regulatory network analysis of phenotypic plasticity in yeast

21.03.2005


Networks are everywhere. Trying to catch connecting flights as we shuttle from one airport to the next can make distances between cities seem even greater than they are. Discovering that you are sitting next to a friend of a friend on one of those flights (social contact networks) can make the world seem a much smaller place. Diverse networks, from airports to social interactions to genes and proteins, often have surprisingly similar structure. In all of these networks, some nodes are highly connected to many other nodes, while most tend to have just a few connections. Molecular biologists have found that the connectedness of genes and proteins is correlated with a range of phenomena, from how essential genes are, to the rates at which they have evolved, to the probability that they are lost over evolutionary time. In the yeast gene regulatory network, some genes are turned on and off by just one ’regulatory gene’ while others are influenced by ten or more regulatory genes. In a study of this network, to be published in the May 2005 issue of American Naturalist, Daniel E. L. Promislow (University of Georgia) now shows that network structure can be used to understand ecological relevant traits.



Promislow analyzes the yeast gene regulatory to understand how genes influence phenotypic plasticity. ’Phenotypic plasticity’ refers to the ability of genetically identical organisms to alter their phenotype in response to an environmental change. For example, genetically identical plants grown in sun versus shade will soon look very different from one another.

It turns out that some species are more plastic than others. Until now, we have not been able to determine what kinds of genes determine whether or not an organism displays phenotypic plasticity. A previous study measured variation in activity level for each of the roughly 6000 genes found in yeast across a range of stressful environments. Some genes varied enormously in their expression levels from one environment to the next, while others were relatively constant. That is, some genes were more plastic than others. Promislow has now discovered that the more regulators a gene has, the more plastic the gene. Furthermore, he shows that the plasticity of a gene depends on its function. From these simple patterns, we gain insight into the complex genetic architecture that determines how well an organism can respond to environmental change.


Carrie Olivia Adams | EurekAlert!
Further information:
http://www.uchicago.edu

More articles from Life Sciences:

nachricht Microscope measures muscle weakness
16.11.2018 | Friedrich-Alexander-Universität Erlangen-Nürnberg

nachricht Good preparation is half the digestion
16.11.2018 | Max-Planck-Institut für Stoffwechselforschung

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: UNH scientists help provide first-ever views of elusive energy explosion

Researchers at the University of New Hampshire have captured a difficult-to-view singular event involving "magnetic reconnection"--the process by which sparse particles and energy around Earth collide producing a quick but mighty explosion--in the Earth's magnetotail, the magnetic environment that trails behind the planet.

Magnetic reconnection has remained a bit of a mystery to scientists. They know it exists and have documented the effects that the energy explosions can...

Im Focus: A Chip with Blood Vessels

Biochips have been developed at TU Wien (Vienna), on which tissue can be produced and examined. This allows supplying the tissue with different substances in a very controlled way.

Cultivating human cells in the Petri dish is not a big challenge today. Producing artificial tissue, however, permeated by fine blood vessels, is a much more...

Im Focus: A Leap Into Quantum Technology

Faster and secure data communication: This is the goal of a new joint project involving physicists from the University of Würzburg. The German Federal Ministry of Education and Research funds the project with 14.8 million euro.

In our digital world data security and secure communication are becoming more and more important. Quantum communication is a promising approach to achieve...

Im Focus: Research icebreaker Polarstern begins the Antarctic season

What does it look like below the ice shelf of the calved massive iceberg A68?

On Saturday, 10 November 2018, the research icebreaker Polarstern will leave its homeport of Bremerhaven, bound for Cape Town, South Africa.

Im Focus: Penn engineers develop ultrathin, ultralight 'nanocardboard'

When choosing materials to make something, trade-offs need to be made between a host of properties, such as thickness, stiffness and weight. Depending on the application in question, finding just the right balance is the difference between success and failure

Now, a team of Penn Engineers has demonstrated a new material they call "nanocardboard," an ultrathin equivalent of corrugated paper cardboard. A square...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

“3rd Conference on Laser Polishing – LaP 2018” Attracts International Experts and Users

09.11.2018 | Event News

On the brain’s ability to find the right direction

06.11.2018 | Event News

European Space Talks: Weltraumschrott – eine Gefahr für die Gesellschaft?

23.10.2018 | Event News

 
Latest News

Purdue cancer identity technology makes it easier to find a tumor's 'address'

16.11.2018 | Health and Medicine

Good preparation is half the digestion

16.11.2018 | Life Sciences

Microscope measures muscle weakness

16.11.2018 | Life Sciences

VideoLinks
Science & Research
Overview of more VideoLinks >>>