A groundbreaking new treatment to combat the hospital killer bug MRSA, which is estimated to cause up to 5,000 deaths a year in Britain, is being developed by a University of Sussex scientist.
Philip Parsons, a professor of organic chemistry, has devised a simple "one-pot" method to make a synthetic version of a natural antibiotic, lactonamycin, which could be used to treat infected patients. He has now received a £280,000 grant from the Engineering and Physical Sciences Research Council towards developing a series of lactonamycin-like substances.
Professor Parsons explains: "The most important thing hospitals can do to fight MRSA is to improve ward cleanliness. But we still need new antibiotics to combat the bug when it arises. "We know that lactonamycin, a naturally occurring antibiotic, can kill MRSA. But it is has not been available as a drug therapy, partly due to its novelty and complexity. We are looking at a simple way to synthesise the antibiotic and its compounds, which could also be highly effective in the fight against infection."
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A widely used diabetes medication combined with an antihypertensive drug specifically inhibits tumor growth – this was discovered by researchers from the University of Basel’s Biozentrum two years ago. In a follow-up study, recently published in “Cell Reports”, the scientists report that this drug cocktail induces cancer cell death by switching off their energy supply.
The widely used anti-diabetes drug metformin not only reduces blood sugar but also has an anti-cancer effect. However, the metformin dose commonly used in the...
A research team from the University of Zurich has developed a new drone that can retract its propeller arms in flight and make itself small to fit through narrow gaps and holes. This is particularly useful when searching for victims of natural disasters.
Inspecting a damaged building after an earthquake or during a fire is exactly the kind of job that human rescuers would like drones to do for them. A flying...
Over the last decade, there has been much excitement about the discovery, recognised by the Nobel Prize in Physics only two years ago, that there are two types...
What if a sensor sensing a thing could be part of the thing itself? Rice University engineers believe they have a two-dimensional solution to do just that.
Rice engineers led by materials scientists Pulickel Ajayan and Jun Lou have developed a method to make atom-flat sensors that seamlessly integrate with devices...
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