Dr. Roger Brent, President and Director of Research at the Molecular Sciences Institute ("MSI"), announced today the release of a new approach to simulation of intracellular biochemical networks in the January edition of Nature Biotechnology.
The research article, entitled "Automatic generation of cellular reaction networks with Moleculizer 1.0," describes MSI’s discrete stochastic event simulator, which keeps track of the thousands of complex species formed from pathway proteins as it simulates reactions between them by a standard Monte Carlo method. A distinguishing aspect of Moleculizer is its ability to generate protein complexes and reactions as they are needed, as opposed to generating all potential complexes and reactions all at once, a task that requires tremendous computational resources.
"Moleculizer is a powerful tool that meets a very real need for biologists," explained Dr. Brent. "It is a critical step forward in our quest to provide an accurate simulation of intracellular biochemical networks."
Maryanne McCormick | EurekAlert!
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