A gene hunt being carried out at the University of Leicester for a skin disorder that affects over one million people in the UK alone has made a new breakthrough which could lead to the design of new and more targeted drugs.
The research team in the University of Leicester Division of Medical Genetics, led by Professor Richard Trembath, has been investigating Psoriasis - an inflammatory skin condition - for a number of years. Now Professor Trembath believes the research has made a ‘significant step’ towards understanding the causes of psoriasis by discovering detailed genetic differences in those afflicted with the disorder.
He said: “In individuals that are genetically predisposed to become affected, the disease can be triggered by a number of environmental agents, such as bacterial infections or stress. We have long been engaged in the search for genes that make people vulnerable to the action of psoriasis-triggering factors. “Our past studies have demonstrated that a small region of what is known as Chromosome 6 contained at least one of such psoriasis susceptibility genes. A closer examination of this genetic interval identified a gene called CDSN, responsible for the adhesion and shedding of skin cells.
Ather Mirza | alfa
Zebrafish's near 360 degree UV-vision knocks stripes off Google Street View
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New cellular pathway helps explain how inflammation leads to artery disease
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Russian researchers together with their French colleagues discovered that a genuine feature of superconductors -- quantum Abrikosov vortices of supercurrent -- can also exist in an ordinary nonsuperconducting metal put into contact with a superconductor. The observation of these vortices provides direct evidence of induced quantum coherence. The pioneering experimental observation was supported by a first-ever numerical model that describes the induced vortices in finer detail.
These fundamental results, published in the journal Nature Communications, enable a better understanding and description of the processes occurring at the...
In a recent publication in the renowned journal Optica, scientists of Leibniz-Institute of Photonic Technology (Leibniz IPHT) in Jena showed that they can accurately control the optical properties of liquid-core fiber lasers and therefore their spectral band width by temperature and pressure tuning.
Already last year, the researchers provided experimental proof of a new dynamic of hybrid solitons– temporally and spectrally stationary light waves resulting...
Scientists from the University of Freiburg and the University of Basel identified a master regulator for bone regeneration. Prasad Shastri, Professor of...
Moving into its fourth decade, AchemAsia is setting out for new horizons: The International Expo and Innovation Forum for Sustainable Chemical Production will take place from 21-23 May 2019 in Shanghai, China. With an updated event profile, the eleventh edition focusses on topics that are especially relevant for the Chinese process industry, putting a strong emphasis on sustainability and innovation.
Founded in 1989 as a spin-off of ACHEMA to cater to the needs of China’s then developing industry, AchemAsia has since grown into a platform where the latest...
The BMBF-funded OWICELLS project was successfully completed with a final presentation at the BMW plant in Munich. The presentation demonstrated a Li-Fi communication with a mobile robot, while the robot carried out usual production processes (welding, moving and testing parts) in a 5x5m² production cell. The robust, optical wireless transmission is based on spatial diversity; in other words, data is sent and received simultaneously by several LEDs and several photodiodes. The system can transmit data at more than 100 Mbit/s and five milliseconds latency.
Modern production technologies in the automobile industry must become more flexible in order to fulfil individual customer requirements.
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