Researchers at New York Universitys Courant Institute of Mathematical Sciences have developed a new algorithm that can lead to more accurate detection of cancer genes than previous versions. The algorithm, published in the latest issue of the Proceedings of the National Academy of Sciences (PNAS), can also be applied to the multiple biomedical technologies (e.g., different kinds of micro-arrays) used to analyze cancer patients genomes.
Headed by NYU Professor Bud Mishra, the research team developed the algorithm to detect the genetic differences between normal cells and cancer cells. Its application reveals several excess as well as missing copies of DNA segments associated with various forms of cancer and ultimately, points to locations of both oncogenes and tumor suppressor genes. In addition, the algorithm can be used to account for the varied genomes present across human population.
An earlier version of the algorithm as well as several other competing algorithms were capable of dealing with only cancer data or only polymorphism data and were unable to separate variations in cancerous and non-cancerous genes in a single framework.
James Devitt | EurekAlert!
Microscope measures muscle weakness
16.11.2018 | Friedrich-Alexander-Universität Erlangen-Nürnberg
Good preparation is half the digestion
16.11.2018 | Max-Planck-Institut für Stoffwechselforschung
Researchers at the University of New Hampshire have captured a difficult-to-view singular event involving "magnetic reconnection"--the process by which sparse particles and energy around Earth collide producing a quick but mighty explosion--in the Earth's magnetotail, the magnetic environment that trails behind the planet.
Magnetic reconnection has remained a bit of a mystery to scientists. They know it exists and have documented the effects that the energy explosions can...
Biochips have been developed at TU Wien (Vienna), on which tissue can be produced and examined. This allows supplying the tissue with different substances in a very controlled way.
Cultivating human cells in the Petri dish is not a big challenge today. Producing artificial tissue, however, permeated by fine blood vessels, is a much more...
Faster and secure data communication: This is the goal of a new joint project involving physicists from the University of Würzburg. The German Federal Ministry of Education and Research funds the project with 14.8 million euro.
In our digital world data security and secure communication are becoming more and more important. Quantum communication is a promising approach to achieve...
On Saturday, 10 November 2018, the research icebreaker Polarstern will leave its homeport of Bremerhaven, bound for Cape Town, South Africa.
When choosing materials to make something, trade-offs need to be made between a host of properties, such as thickness, stiffness and weight. Depending on the application in question, finding just the right balance is the difference between success and failure
Now, a team of Penn Engineers has demonstrated a new material they call "nanocardboard," an ultrathin equivalent of corrugated paper cardboard. A square...
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16.11.2018 | Life Sciences