Columbia University Medical Center and Albert Einstein College of Medicine researchers have identified a possible cause of an inherited form of Parkinson’s disease, which may be related to more common forms of the disease. The findings are reported in the August 27, 2004 issue of Science.
While the cause of most cases of Parkinson’s disease is unknown, a few cases are inherited and can be traced to mutations in four different genes, including the alpha-synuclein gene. This is the first study that may pinpoint the mechanism by which the mutant gene initiates a cascade of events that causes this devastating neurological disease.
"This discovery could aid in the development of new, targeted treatments to slow or stop the disease progression," said David Sulzer, Ph.D., professor of neurology and psychiatry at Columbia University College of Physicians and Surgeons and senior author of the study. "This is an extension of the genetic research that discovered the mutant alpha-synuclein gene and it is exciting to see how this information can be used to possibly determine the cause of Parkinson’s disease."
Elizabeth Streich | EurekAlert!
UNH researchers create a more effective hydrogel for healing wounds
21.11.2018 | University of New Hampshire
Removing toxic mercury from contaminated water
21.11.2018 | Chalmers University of Technology
Innsbruck quantum physicists have constructed a diode for magnetic fields and then tested it in the laboratory. The device, developed by the research groups led by the theorist Oriol Romero-Isart and the experimental physicist Gerhard Kirchmair, could open up a number of new applications.
Electric diodes are essential electronic components that conduct electricity in one direction but prevent conduction in the opposite one. They are found at the...
Max Planck researchers revel the nano-structure of molecular trains and the reason for smooth transport in cellular antennas.
Moving around, sensing the extracellular environment, and signaling to other cells are important for a cell to function properly. Responsible for those tasks...
Researchers at the University of New Hampshire have captured a difficult-to-view singular event involving "magnetic reconnection"--the process by which sparse particles and energy around Earth collide producing a quick but mighty explosion--in the Earth's magnetotail, the magnetic environment that trails behind the planet.
Magnetic reconnection has remained a bit of a mystery to scientists. They know it exists and have documented the effects that the energy explosions can...
Biochips have been developed at TU Wien (Vienna), on which tissue can be produced and examined. This allows supplying the tissue with different substances in a very controlled way.
Cultivating human cells in the Petri dish is not a big challenge today. Producing artificial tissue, however, permeated by fine blood vessels, is a much more...
Faster and secure data communication: This is the goal of a new joint project involving physicists from the University of Würzburg. The German Federal Ministry of Education and Research funds the project with 14.8 million euro.
In our digital world data security and secure communication are becoming more and more important. Quantum communication is a promising approach to achieve...
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