When a dendritic cell meets a T cell… The dendritic cell and its “arms” can be seen on the left of the images. On the right is a smaller T cell. In the first image, the dendritic cell reaches out in search of a T cell. In the second image, it finds a T cell and extends its arms towards it. In the third image, the dendritic cell entraps the T cell. © F. Benvenuti/Institut Curie
In this dendritic cell, the proteins Rac 1 and 2 are inactive. The dendritic cell is "unaware" of the presence of the T cell. © F. Benvenuti/Institut Curie
The dendritic cells act as the body’s sentries, standing guard around the clock. As soon as they detect a potential enemy, they alert the T cells, whose role is to defend the body.
At the Institut Curie, CNRS researchers in an Inserm laboratory have filmed the encounter of dendritic cells and T cells. They have shown that this "rendez-vous", which is indispensable for the activation of the immune system, cannot take place in the absence of the proteins Rac 1 and 2. Published in the August 20, 2004 issue of Science, this discovery yields new information on the immune system and could in time pave the way for advances in immunotherapy.
Our immune system is on call round the clock. Whenever a foreign body intrudes (virus, bacterium…), or even in response to the anarchic proliferation of the body’s own cells (cancer), the immune system sounds the alarm.
Catherine Goupillon | alfa
Overlooked molecular machine in cell nucleus may hold key to treating aggressive leukemia
23.04.2019 | Cincinnati Children's Hospital Medical Center
Bacteria use their enemy -- phage -- for 'self-recognition'
23.04.2019 | Chinese Academy of Sciences Headquarters
Researchers led by Francesca Ferlaino from the University of Innsbruck and the Austrian Academy of Sciences report in Physical Review X on the observation of supersolid behavior in dipolar quantum gases of erbium and dysprosium. In the dysprosium gas these properties are unprecedentedly long-lived. This sets the stage for future investigations into the nature of this exotic phase of matter.
Supersolidity is a paradoxical state where the matter is both crystallized and superfluid. Predicted 50 years ago, such a counter-intuitive phase, featuring...
A stellar flare 10 times more powerful than anything seen on our sun has burst from an ultracool star almost the same size as Jupiter
A localization phenomenon boosts the accuracy of solving quantum many-body problems with quantum computers which are otherwise challenging for conventional computers. This brings such digital quantum simulation within reach on quantum devices available today.
Quantum computers promise to solve certain computational problems exponentially faster than any classical machine. “A particularly promising application is the...
The technology could revolutionize how information travels through data centers and artificial intelligence networks
Engineers at the University of California, Berkeley have built a new photonic switch that can control the direction of light passing through optical fibers...
Physicists observe how electron-hole pairs drift apart at ultrafast speed, but still remain strongly bound.
Modern electronics relies on ultrafast charge motion on ever shorter length scales. Physicists from Regensburg and Gothenburg have now succeeded in resolving a...
17.04.2019 | Event News
15.04.2019 | Event News
09.04.2019 | Event News
24.04.2019 | Trade Fair News
23.04.2019 | Information Technology
23.04.2019 | Earth Sciences