When a dendritic cell meets a T cell… The dendritic cell and its “arms” can be seen on the left of the images. On the right is a smaller T cell. In the first image, the dendritic cell reaches out in search of a T cell. In the second image, it finds a T cell and extends its arms towards it. In the third image, the dendritic cell entraps the T cell. © F. Benvenuti/Institut Curie
In this dendritic cell, the proteins Rac 1 and 2 are inactive. The dendritic cell is "unaware" of the presence of the T cell. © F. Benvenuti/Institut Curie
The dendritic cells act as the body’s sentries, standing guard around the clock. As soon as they detect a potential enemy, they alert the T cells, whose role is to defend the body.
At the Institut Curie, CNRS researchers in an Inserm laboratory have filmed the encounter of dendritic cells and T cells. They have shown that this "rendez-vous", which is indispensable for the activation of the immune system, cannot take place in the absence of the proteins Rac 1 and 2. Published in the August 20, 2004 issue of Science, this discovery yields new information on the immune system and could in time pave the way for advances in immunotherapy.
Our immune system is on call round the clock. Whenever a foreign body intrudes (virus, bacterium…), or even in response to the anarchic proliferation of the body’s own cells (cancer), the immune system sounds the alarm.
Catherine Goupillon | alfa
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A new research project at the TH Mittelhessen focusses on the development of a novel light weight design concept for leisure boats and yachts. Professor Stephan Marzi from the THM Institute of Mechanics and Materials collaborates with Krake Catamarane, which is a shipyard located in Apolda, Thuringia.
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Superconductivity has fascinated scientists for many years since it offers the potential to revolutionize current technologies. Materials only become superconductors - meaning that electrons can travel in them with no resistance - at very low temperatures. These days, this unique zero resistance superconductivity is commonly found in a number of technologies, such as magnetic resonance imaging (MRI).
Future technologies, however, will harness the total synchrony of electronic behavior in superconductors - a property called the phase. There is currently a...
How do some neutron stars become the strongest magnets in the Universe? A German-British team of astrophysicists has found a possible answer to the question of how these so-called magnetars form. Researchers from Heidelberg, Garching, and Oxford used large computer simulations to demonstrate how the merger of two stars creates strong magnetic fields. If such stars explode in supernovae, magnetars could result.
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A hot, molten Earth would be around 5% larger than its solid counterpart. This is the result of a study led by researchers at the University of Bern. The difference between molten and solid rocky planets is important for the search of Earth-like worlds beyond our Solar System and the understanding of Earth itself.
Rocky exoplanets that are around Earth-size are comparatively small, which makes them incredibly difficult to detect and characterise using telescopes. What...
Scientists at the Max Planck Institute for Chemical Physics of Solids in Dresden, Princeton University, the University of Illinois at Urbana-Champaign, and the University of the Chinese Academy of Sciences have spotted a famously elusive particle: The axion – first predicted 42 years ago as an elementary particle in extensions of the standard model of particle physics.
The team found signatures of axion particles composed of Weyl-type electrons (Weyl fermions) in the correlated Weyl semimetal (TaSe₄)₂I. At room temperature,...
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