Babraham Institute scientists have identified chromosome ‘loops’ which have implications for healthy growth of babies in the womb. Disruption of these loops can lead to Beckwith-Wiedemann Syndrome (BWS) – over-large babies with various tumours – which affects 1 in 13,000 births. The risk of developing the syndrome is increased four-fold in babies born following IVF treatment.
Confirmation of the existence of the loops, described in an article published in Nature Genetics, was made by Dr Adele Murrell and colleagues, working with Dr Wolf Reik at the Babraham Institute. Scientists had previously speculated that these loops, or something similar, exist, but no-one had evidence to prove this was the case.
Dr Reik’s group studies imprinted genes, which are genes in mammals that are only expressed from one of the parental chromosomes. These genes have important roles in regulating the growth of the baby in the womb and its adaptations to life outside the womb. Many of them occur in clusters, and share elements by which their expression can be increased (enhancers) or decreased (silencers).
Emma Southern | alfa
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Researchers at the University of New Hampshire have captured a difficult-to-view singular event involving "magnetic reconnection"--the process by which sparse particles and energy around Earth collide producing a quick but mighty explosion--in the Earth's magnetotail, the magnetic environment that trails behind the planet.
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Faster and secure data communication: This is the goal of a new joint project involving physicists from the University of Würzburg. The German Federal Ministry of Education and Research funds the project with 14.8 million euro.
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On Saturday, 10 November 2018, the research icebreaker Polarstern will leave its homeport of Bremerhaven, bound for Cape Town, South Africa.
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20.11.2018 | Life Sciences
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