A gigantic protein complex responsible for looking after bent out of shape proteins has been visualised by scientists working in Japan and the UK.
The structure of the chaperonin complex of the bacteria Thermus thermophilus reveals clues about how the important molecule may do its job of folding new or damaged proteins within cells. Led by Professor So Iwata of Imperial College London, the team of scientists announce their findings in this months edition of the journal Structure (August 2004).
The complex comprises three separate parts - two identical cage units lashed back to back, and a cap unit that sits atop the cage, acting as a stopper. The cage contains the unwound, or denatured, protein, while the chaperonin goes about refolding its shape using the cellular energy source, ATP.
Unravelling the genetics of fungal fratricide
16.10.2018 | Uppsala University
Fungal weapon turns against the maker
16.10.2018 | Leibniz-Institut für Naturstoff-Forschung und Infektionsbiologie - Hans-Knöll-Institut (HKI)
Augsburg chemists present a new technology for compressing, storing and transporting highly volatile gases in porous frameworks/New prospects for gas-powered vehicles
Storage of highly volatile gases has always been a major technological challenge, not least for use in the automotive sector, for, for example, methane or...
When we put water in a freezer, water molecules crystallize and form ice. This change from one phase of matter to another is called a phase transition. While this transition, and countless others that occur in nature, typically takes place at the same fixed conditions, such as the freezing point, one can ask how it can be influenced in a controlled way.
We are all familiar with such control of the freezing transition, as it is an essential ingredient in the art of making a sorbet or a slushy. To make a cold...
Thin organic layers provide machines and equipment with new functions. They enable, for example, tiny energy recuperators. In future, these will be installed...
Das Zusammenspiel aus Struktur und Dynamik bestimmt die Funktion von Proteinen, den molekularen Werkzeugen der Zelle. Durch Fortschritte in der...
New measurement method allows researchers to precisely follow the movement of individual molecules over long periods of time
The function of proteins – the molecular tools of the cell – is governed by the interplay of their structure and dynamics. Advances in electron microscopy have...
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