At his presentation at the annual meeting of the American Society of Plant Biologists (ASPB) here July 24, 2004, Arizona State University Professor Charles J. Arntzen explained the newest advances in his research on plant-producing vaccines.
The development and introduction of new vaccines to improve global public health faces many challenges, Arntzen noted. The vaccines must address the need for lower costs, oral-administration (needle-free), heat stability, and they must include combination vaccines including those that protect against diseases that occur predominantly in developing countries, he added.
Over the last decade, the team working with Arntzen has shown that a set of genes from human pathogens can be introduced into plant cells, and intact plants regenerated which "bio-manufacture" subunit vaccines consisting of the pathogen gene products. Simple feeding of the plant tissues to animals or humans results in an immune response to the subunit vaccines," Arntzen commented.
Brian Hyps | EurekAlert!
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