A team of researchers from the University Hospital of Grenoble (CHU – Inserm U647) and the ESRF1 has found a new treatment that improves the survival of rats with high-grade gliomas.
This research was carried out at the ESRF Medical Beamline. It showed that after a year of this treatment, three rats out of 10 were considered cured, whereas without treatment, all would be dead. The results have just been published in the scientific journal Cancer Research. A glioma is one of the most frequent brain tumours in human adults, and it is not curable. Clinical trials on humans are planned for the near future.
Today, the median survival for patients with glioma is less than a year. Around 5 to 10 adults out of 100.000 suffer from this brain tumour. Traditional radiotherapy using hospital X-rays only has a palliative effect because gliomas are some of the most radio-resistant human tumours. Chemotherapy is ineffective most of the time. Several therapeutic techniques have been developed over the last years using animal models, but none has had such successful results as this new treatment with cis-platinum combined with monochromatic synchrotron x-rays. This new technique combines chemotherapy with radiotherapy in such a way that both techniques are effective when associated.
Montserrat Capellas | alfa
Nanocages in the lab and in the computer: how DNA-based dendrimers transport nanoparticles
19.10.2018 | University of Vienna
Less animal experiments on the horizon: Multi-organ chip awarded
19.10.2018 | Fraunhofer-Institut für Werkstoff- und Strahltechnik IWS
Scientists at the Max Planck Institute for Polymer Research (MPI-P) in Mainz (Germany) together with scientists from Dresden, Leipzig, Sofia (Bulgaria) and Madrid (Spain) have now developed and characterized a novel, metal-organic material which displays electrical properties mimicking those of highly crystalline silicon. The material which can easily be fabricated at room temperature could serve as a replacement for expensive conventional inorganic materials used in optoelectronics.
Silicon, a so called semiconductor, is currently widely employed for the development of components such as solar cells, LEDs or computer chips. High purity...
Augsburg chemists present a new technology for compressing, storing and transporting highly volatile gases in porous frameworks/New prospects for gas-powered vehicles
Storage of highly volatile gases has always been a major technological challenge, not least for use in the automotive sector, for, for example, methane or...
When we put water in a freezer, water molecules crystallize and form ice. This change from one phase of matter to another is called a phase transition. While this transition, and countless others that occur in nature, typically takes place at the same fixed conditions, such as the freezing point, one can ask how it can be influenced in a controlled way.
We are all familiar with such control of the freezing transition, as it is an essential ingredient in the art of making a sorbet or a slushy. To make a cold...
Thin organic layers provide machines and equipment with new functions. They enable, for example, tiny energy recuperators. In future, these will be installed...
Das Zusammenspiel aus Struktur und Dynamik bestimmt die Funktion von Proteinen, den molekularen Werkzeugen der Zelle. Durch Fortschritte in der...
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