High quality outcomes allow researchers to identify cancer-related genetic changes that span years
For the first time, Fox Chase Cancer Center researchers have demonstrated the ability to extract RNA from formalin-fixed, paraffin-embedded tissue samples archived for up to five years. Whats more, the technology used retrieves high-quality samples, allowing researchers to identify cancer-related genetic changes. Accepted as a "late-breaking" abstract, the research was presented today at the 95th Annual Meeting of the American Association for Cancer Research by Renata Coudry, M.D., a research pathologist at Fox Chase Cancer Center.
"Recent advances in both laser-capture microdissection (LCM) technology and microarray technology have revolutionized our investigation of the genetic basis of human cancer," said Coudry. "Pure cell populations can now be isolated by LCM and evaluated for changes in gene expression that accompany the development of cancer. However, applying these techniques to archived clinical specimens has been limited by our inability to extract high-quality genetic material from routinely processed clinical samples."
Karen Carter Mallet | EurekAlert!
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A new manufacturing technique uses a process similar to newspaper printing to form smoother and more flexible metals for making ultrafast electronic devices.
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For the first time a team of researchers have discovered two different phases of magnetic skyrmions in a single material. Physicists of the Technical Universities of Munich and Dresden and the University of Cologne can now better study and understand the properties of these magnetic structures, which are important for both basic research and applications.
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Physicists working with Roland Wester at the University of Innsbruck have investigated if and how chemical reactions can be influenced by targeted vibrational excitation of the reactants. They were able to demonstrate that excitation with a laser beam does not affect the efficiency of a chemical exchange reaction and that the excited molecular group acts only as a spectator in the reaction.
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Optical spectroscopy allows investigating the energy structure and dynamic properties of complex quantum systems. Researchers from the University of Würzburg present two new approaches of coherent two-dimensional spectroscopy.
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