Viruses, often able to outsmart many of the drugs designed to defeat them, may have met their match, according to new research from the University of Wisconsin-Madison.
The findings show that the introduction of a harmless molecule that uses the same machinery a virus needs to grow may be a potent way to shut down the virus before it infects other cells or becomes resistant to drugs. The results are published in the March issue of the journal, Antimicrobial Agents and Chemotherapy.
"When a virus encounters a susceptible cell, it enters and says, Im now the boss," explains John Yin, a UW-Madison associate professor of chemical and biological engineering and senior author of the paper. "It pirates the cells resources to produce virus progeny that, following release from the host cell, can infect other cells."
Emily Carlson | EurekAlert!
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