Researchers at the Center for Biomedical Inventions at UT Southwestern Medical Center at Dallas have identified the genetic changes that Mycobacterium tuberculosis, the bacterium that causes tuberculosis, undergoes during infection of a living host.
For the first time, researchers have adapted gene-chip technology to carry out genomic analysis of gene expression during the course of infection not only for M. tuberculosis, but for any pathogen. The findings will appear in an upcoming issue of the Proceedings of the National Academy of Sciences and are currently available online.
To analyze multiple questions about the pathogenesis of tuberculosis, the researchers used gene chips, which allowed them to assess the pattern in which bacterial genes are expressed during the course of infection. This work demanded two years of technology development to establish a protocol that allowed high-throughput analysis of genes that were expressed in a pathogen that was extracted from an infected animal, rather than simply grown in culture.
Steve O’Brien | EurekAlert!
Dissolving protein traffic jam at the entrance of mitochondria
23.05.2019 | Albert-Ludwigs-Universität Freiburg im Breisgau
Producing tissue and organs through lithography
23.05.2019 | Goethe-Universität Frankfurt am Main
Physicists at the University of Basel are able to show for the first time how a single electron looks in an artificial atom. A newly developed method enables them to show the probability of an electron being present in a space. This allows improved control of electron spins, which could serve as the smallest information unit in a future quantum computer. The experiments were published in Physical Review Letters and the related theory in Physical Review B.
The spin of an electron is a promising candidate for use as the smallest information unit (qubit) of a quantum computer. Controlling and switching this spin or...
Engineers at the University of Tokyo continually pioneer new ways to improve battery technology. Professor Atsuo Yamada and his team recently developed a...
With a quantum coprocessor in the cloud, physicists from Innsbruck, Austria, open the door to the simulation of previously unsolvable problems in chemistry, materials research or high-energy physics. The research groups led by Rainer Blatt and Peter Zoller report in the journal Nature how they simulated particle physics phenomena on 20 quantum bits and how the quantum simulator self-verified the result for the first time.
Many scientists are currently working on investigating how quantum advantage can be exploited on hardware already available today. Three years ago, physicists...
'Quantum technologies' utilise the unique phenomena of quantum superposition and entanglement to encode and process information, with potentially profound benefits to a wide range of information technologies from communications to sensing and computing.
However a major challenge in developing these technologies is that the quantum phenomena are very fragile, and only a handful of physical systems have been...
Working group led by physicist Professor Ulrich Nowak at the University of Konstanz, in collaboration with a team of physicists from Johannes Gutenberg University Mainz, demonstrates how skyrmions can be used for the computer concepts of the future
When it comes to performing a calculation destined to arrive at an exact result, humans are hopelessly inferior to the computer. In other areas, humans are...
29.04.2019 | Event News
17.04.2019 | Event News
15.04.2019 | Event News
23.05.2019 | Materials Sciences
23.05.2019 | Materials Sciences
23.05.2019 | Physics and Astronomy