Different combinations of genetic mutations may give rise to diverse human traits, including complex diseases such as schizophrenia, say scientists at the University of Toronto and McGill University in Montreal.
Drs. Brenda Andrews and Charles Boone of U of T and Howard Bussey of McGill used simple yeast cells to demonstrate that there are many different combinations of genetic mutations that can lead to cell death or reduced cell fitness. The research team will now focus on mapping gene interactions for those yeast genes that are similar to human genes. Their study appears in the Feb. 6 issue of the journal Science.
The researchers crossed a yeast strain carrying a mutation in a particular gene of interest with a collection or "array" of other yeast strains to determine which gene pairs were lethal. The team studied more than 4,000 of these interactions involving gene pairs and was able to provide a large scale "genetic interaction network" that provokes new ideas about how genes interact to produce different traits.
Elaine Smith | University of Toronto
Microscope measures muscle weakness
16.11.2018 | Friedrich-Alexander-Universität Erlangen-Nürnberg
Good preparation is half the digestion
16.11.2018 | Max-Planck-Institut für Stoffwechselforschung
Researchers at the University of New Hampshire have captured a difficult-to-view singular event involving "magnetic reconnection"--the process by which sparse particles and energy around Earth collide producing a quick but mighty explosion--in the Earth's magnetotail, the magnetic environment that trails behind the planet.
Magnetic reconnection has remained a bit of a mystery to scientists. They know it exists and have documented the effects that the energy explosions can...
Biochips have been developed at TU Wien (Vienna), on which tissue can be produced and examined. This allows supplying the tissue with different substances in a very controlled way.
Cultivating human cells in the Petri dish is not a big challenge today. Producing artificial tissue, however, permeated by fine blood vessels, is a much more...
Faster and secure data communication: This is the goal of a new joint project involving physicists from the University of Würzburg. The German Federal Ministry of Education and Research funds the project with 14.8 million euro.
In our digital world data security and secure communication are becoming more and more important. Quantum communication is a promising approach to achieve...
On Saturday, 10 November 2018, the research icebreaker Polarstern will leave its homeport of Bremerhaven, bound for Cape Town, South Africa.
When choosing materials to make something, trade-offs need to be made between a host of properties, such as thickness, stiffness and weight. Depending on the application in question, finding just the right balance is the difference between success and failure
Now, a team of Penn Engineers has demonstrated a new material they call "nanocardboard," an ultrathin equivalent of corrugated paper cardboard. A square...
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16.11.2018 | Life Sciences