Researchers have discovered that a specific type of calcium channel -- a pore-like protein that nestles in the cell membrane and controls the flow of calcium into the cell -- regulates the relaxation of coronary arteries.
The studies showed that mice engineered to lack these calcium channels had constricted coronary arteries and had fibrous tissue in their hearts, which was evident when the animals hearts reacted to chronic blood restriction. The researchers hypothesize that drugs targeting this calcium channel might one day be used to treat cardiovascular disease by opening arteries.
The researchers, led by Howard Hughes Medical Institute investigator Kevin Campbell, published their findings in the November 21, 2003, issue of the journal Science. Campbell and his colleagues at the University of Iowa collaborated with researchers from the Veterans Administration Medical Center in Iowa City, Loyola University Medical Center and the University of Texas Southwestern Medical Center.
Jim Keeley | EurekAlert!
Catalysts for climate protection
19.08.2019 | Fraunhofer-Institut für Grenzflächen- und Bioverfahrenstechnik IGB
From the tiny testes of flies, new insight into how genes arise
19.08.2019 | Rockefeller University
Soft robots have a distinct advantage over their rigid forebears: they can adapt to complex environments, handle fragile objects and interact safely with humans. Made from silicone, rubber or other stretchable polymers, they are ideal for use in rehabilitation exoskeletons and robotic clothing. Soft bio-inspired robots could one day be deployed to explore remote or dangerous environments.
Most soft robots are actuated by rigid, noisy pumps that push fluids into the machines' moving parts. Because they are connected to these bulky pumps by tubes,...
Researchers at TU Graz are working together with European partners on new possibilities of measuring vehicle emissions.
Today, air pollution is one of the biggest challenges facing European cities. As part of the Horizon 2020 research project CARES (City Air Remote Emission...
Over the next three years, researchers from the Vrije Universiteit Brussel, University of Cambridge, École Supérieure de Physique et de Chimie Industrielles de la ville de Paris (ESPCI-Paris) and Empa will be working together with the Dutch Polymer manufacturer SupraPolix on the next generation of robots: (soft) robots that ‘feel pain’ and heal themselves. The partners can count on 3 million Euro in support from the European Commission.
Soon robots will not only be found in factories and laboratories, but will be assisting us in our immediate environment. They will help us in the household, to...
Scientists at the University of Leeds have created a new form of gold which is just two atoms thick - the thinnest unsupported gold ever created.
The researchers measured the thickness of the gold to be 0.47 nanometres - that is one million times thinner than a human finger nail. The material is regarded...
An international team of scientists involving the Max Planck Institute for the Structure and Dynamics of Matter (MPSD) in Hamburg has unraveled the light-induced electron-localization dynamics in transition metals at the attosecond timescale. The team investigated for the first time the many-body electron dynamics in transition metals before thermalization sets in. Their work has now appeared in Nature Physics.
The researchers from ETH Zurich (Switzerland), the MPSD (Germany), the Center for Computational Sciences of University of Tsukuba (Japan) and the Center for...
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